To describe the prevalence of allergic sensitization to Storage Dust Mites (SDM), access whether the place of living and occupational exposure were determinants for SDM sensitization and study association between Lepidoglyphus destructor and other SDM sensitization. Prospective analysis of patients evaluated for suspected allergic rhinitis and/or asthma that performed Skin Prick Tests (SPT) to SDM between January and December 2018 in our Department. Two hundred consecutive patients were evaluated for rhinitis and/or asthma in our outpatient consultation: 123 (61.5%) presented positivity for at least one SDM, 68.3% were female and the mean age was 33.1 ± 12.12. (69.9%) was the most prevalent, followed by (50.4%), and (48.8%) and (24.4%). Living in a rural place was not associated with a higher prevalence of sensitization to SDM, except for (p = 0.032), and working in a place with storage areas was not associated with sensitization to any of SDM. Sensitization to was associated with sensitization to , and (p less than 0.005), but not with Our study suggests that our population, independently of their occupational exposure and place of residency, are sensitized to SDM and that evaluation of sensitization to SDM should be considered as standard practice.
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.178 | DOI Listing |
Adv Healthc Mater
May 2024
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Nat Commun
March 2023
Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-containing amino acid cysteine, and indirectly from methionine via the transsulfuration pathway. Herein we show that cysteine and methionine deprivation (CMD) can synergize with the GPX4 inhibitor RSL3 to increase ferroptotic cell death and lipid peroxidation in both murine and human glioma cell lines and in ex vivo organotypic slice cultures.
View Article and Find Full Text PDFEur Ann Allergy Clin Immunol
January 2022
Department of Allergy and Clinical Immunology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
To describe the prevalence of allergic sensitization to Storage Dust Mites (SDM), access whether the place of living and occupational exposure were determinants for SDM sensitization and study association between Lepidoglyphus destructor and other SDM sensitization. Prospective analysis of patients evaluated for suspected allergic rhinitis and/or asthma that performed Skin Prick Tests (SPT) to SDM between January and December 2018 in our Department. Two hundred consecutive patients were evaluated for rhinitis and/or asthma in our outpatient consultation: 123 (61.
View Article and Find Full Text PDFJ Immunol Res
July 2021
Department of Food Science and Technology, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.
This study was conducted to evaluate the effects of recombinant probiotic bacteria as a candidate for oral vaccine with the potential of treating allergy to pollens. The main gene of this allergen, Ama r 2, was cloned into the food grade plasmid pNZ7025 and then was electrotransformed into the food grade NZ1330. No expression was observed in the primary structure due to the distance between the ribosome binding site and the start codon.
View Article and Find Full Text PDFOral Maxillofac Surg Clin North Am
August 2018
Department of Diagnostic Sciences, Center for Temporomandiublar Disorders and Orofacial Pain, Rutgers School of Dental Medicine, Room D880, 110 Bergen Street, Newark, NJ 07101, USA. Electronic address:
This is not a pharmacopeia offering directions for choosing the proper pain medication for treating temporomandibular disorders. Rather, the appropriate decision depends on proper diagnosis, an understanding of the pain mechanisms involved, and the different targets for analgesic action. This article discusses these issues and evaluates the various drugs involved.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!