AI Article Synopsis

  • This narrative review examines the reasons for performing elective and therapeutic neck dissections in patients with well-differentiated thyroid cancer, along with follow-up and treatment options for recurrent nodal disease.
  • Recent advancements in imaging have led to better detection of nodal metastases, which are more prevalent in younger patients and those with larger tumors or specific genetic and histological profiles.
  • While visible nodal disease correlates with worse patient outcomes and should be surgically addressed to minimize recurrence, the significance of microscopic metastases on overall survival remains limited, questioning the need for elective neck dissections.

Article Abstract

Purpose Of Review: In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer.

Recent Findings: Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500240PMC
http://dx.doi.org/10.1007/s11912-020-00997-6DOI Listing

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