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http://dx.doi.org/10.1016/j.jaip.2020.10.055 | DOI Listing |
J Contemp Dent Pract
September 2024
Department of Conservative Dentistry and Endodontics, PMNM Dental College and Hospital, Bagalkot, Karnataka, India.
Aim: The present study is aimed to compare the effectiveness of dentinal tubule occlusion of two natural-based desensitizing toothpaste (Bentodent Desensitizer and Fang Farm Mint) and Novamin-based toothpaste (Shy-NM) under scanning electron microscope (SEM).
Materials And Methods: A total of 60 root dentin discs (3 mm-thick) were obtained from recently extracted permanent premolar teeth and were randomly divided into four groups based on the desensitizing toothpaste used, each group with 15 samples: Group I: Control, group II: Shy-NM, group III: Bentodent desensitizer, group IV: Fang Farm Mint. Samples were brushed for 2 min twice daily with a soft toothbrush with respective pea size amount of toothpaste for 14 days manually.
Cochrane Database Syst Rev
January 2025
Department of Otorhinolaryngology, Amsterdam University Medical Centre, Amsterdam, Netherlands.
Background: NSAID-exacerbated respiratory disease (N-ERD) is a hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, accompanied by chronic rhinosinusitis (with or without nasal polyps) or asthma. The prevalence of hypersensitivity to NSAIDs is estimated to be 2%. The first line of treatment is the avoidance of NSAIDs.
View Article and Find Full Text PDFJ Clin Med
December 2024
Allergology Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
is a topoisomerase I inhibitor used for the treatment of various cancers, such as gastrointestinal, pancreatic, pulmonary, ovarian, and cervical cancers. Among chemotherapy agents, it represents a rare trigger of drug hypersensitivity reactions, with few cases being reported until today. We present the case of a patient with metastatic esophageal cancer and a history of -induced grade IV (WAO classification) anaphylaxis.
View Article and Find Full Text PDFJ Addict Med
January 2025
From the Boonshoft School of Medicine, Wright State University, Dayton, OH (KL, SS, TNC); Ohio State University, Columbus, OH (SH, NM, TP); and RTI International, Research Triangle Park, NC (BR).
Objectives: Stigma is known to be a major barrier to treatment for people who use drugs (PWUD). This study uses the Stigma and Health Discrimination Framework to analyze how different forms of stigma shape experiences in the wake of an overdose incident, and perceptions of the efficacy and utility of postoverdose interventions among a sample of PWUD in Dayton, Ohio-a location with a high overdose rate.
Methods: Interviews were conducted with 23 individuals who self-reported past-month illicit opioid, crack/cocaine, or methamphetamine use who had experienced or witnessed a drug overdose in the past 6 months.
Sci Rep
January 2025
Department of Biomedical Engineering, Graduate School of Medicine, Science and Technology, Shinshu University, Nagano, 390-8621, Japan.
Lysophosphatidylethanolamine (LPE) is a bioactive lipid mediator involved in diverse cellular functions. In this study, we investigated the effects of three LPE species, 1-palmitoyl LPE (16:0 LPE), 1-stearoyl LPE (18:0 LPE), and 1-oleoyl LPE (18:1 LPE) on pre-osteoblast MC3T3-E1 cells. All LPE species stimulated cell proliferation and activated the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) 1/2.
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