AI Article Synopsis
- L. has a longstanding and controversial history as a cultivated crop, gaining new significance in Canada for both medicinal and recreational use due to recent legalization.
- Advances in genome sequencing of cannabis and hemp have facilitated the study of genes related to cannabinoid production, highlighting the pivotal role of single-nucleotide polymorphisms in cannabinoid synthase genes that influence plant characteristics.
- A detailed understanding of how these genetic variants impact enzyme function and cannabinoid levels could lead to the development of specialized plant cultivars with desirable properties.
Article Abstract
Despite being a controversial crop, L. has a long history of cultivation throughout the world. Following recent legalization in Canada, is emerging as an important plant for both medicinal and recreational purposes. Recent progress in genome sequencing of both cannabis and hemp varieties allow for systematic analysis of genes coding for enzymes involved in the cannabinoid biosynthesis pathway. Single-nucleotide polymorphisms in the coding regions of cannabinoid synthases play an important role in determining plant chemotype. Deep understanding of how these variants affect enzyme activity and accumulation of cannabinoids will allow breeding of novel cultivars with desirable cannabinoid profiles. Here we present a short overview of the major cannabinoid synthases and present the data on the analysis of their genetic variants and their effect on cannabinoid content using several in-house sequenced cultivars.
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| http://dx.doi.org/10.1139/gen-2020-0087 | DOI Listing |
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