AI Article Synopsis
- Prostate cancer (PCa) is a significant public health issue, being a major cause of illness and death globally, while coronary artery disease (CAD) is the top cause of death worldwide.
- The review examines how both modifiable and non-modifiable risk factors contribute to these conditions, highlighting the link between high cholesterol levels (a CAD risk factor) and PCa.
- It suggests that patients with atherosclerosis should be screened for PCa, and those with PCa should be checked for cardiovascular diseases; additionally, statins might help in managing atherosclerosis and reducing PCa risk.
Article Abstract
Prostate cancer (PCa) remains a relevant public health concern and one of the main causes of morbidity and mortality worldwide. Coronary artery disease (CAD) with the underlying coronary artery atherosclerosis is the leading cause of global death. The interaction between modifiable and non-modifiable risk factors for these pathological conditions is discussed in the review. Elevated serum cholesterol, a known risk factor for CAD, can be associated with both development and progression of PCa. From this perspective, patients with atherosclerosis may represent a potential target group for PCa screening. Alternatively, patients with PCa should undergo examination for concomitant cardiovascular diseases as well as their risk factors. Statins are supposed to be potentially beneficial in treating atherosclerosis in men and reducing the risk of PCa development and progression.
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