Numerous reports describe the antioxidant and antimicrobial activity of polyphenols-rich plant extracts. The aim of this study was to determine the total polyphenols content (TPC), and the (DPPH, FRAP and TEAC) antioxidant and antibacterial activity of leaves and wood of six native woody species (t, , , , and ) from Catamarca. Also, the phenolic profile was determined in the species with higher activity. leaf extracts showed the highest antioxidant activity followed by and while wood extracts showed the highest. Furthermore, species showed antibacterial activity against and strains showing cidal effects mainly against . Fifty-nine polyphenols were identified in leaves and wood of and . species, which are likely to be responsible for the different activities observed.
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http://dx.doi.org/10.1080/14786419.2020.1839461 | DOI Listing |
Food Chem
December 2024
Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830017, China. Electronic address:
This study developed antimicrobial peptides (AMPs) from quinoa with high antibacterial activity and stability by mixed-bacteria fermentation. Furthermore, among 9 peptide fractions purified by membrane separation and chromatography, F1 could effectively inhibit the growth and propagation of bacterial microorganisms in apple juice. Subsequently, F1 identified LC-MS/MS as 95 peptides, molecular weights 494.
View Article and Find Full Text PDFMol Pharm
December 2024
Department of Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Gallium, a trace metal not found in its elemental form in nature, has garnered significant interest as a biocide, given its ability to interfere with iron metabolism in bacteria. Consequently, several gallium compounds have been developed and studied for their antimicrobial properties but face challenges of poor solubility and formulation for delivery. Organizing the metal into three-dimensional, hybrid scaffolds, termed metal-organic frameworks (MOFs), is an emerging platform with potential to address many of these limitations.
View Article and Find Full Text PDFMol Divers
December 2024
Guizhou Engineering Research Center for Characteristic Flavor Perception and Quality Control of Drug-Food Homologous Resources, Guiyang University, Guiyang, 550005, People's Republic of China.
Natural compounds' derivatives as lead structures could effectively solve plant disease problems. In this article, amide compounds and amide ester compounds were synthetized through ferulic acid as the parent nucleus structure, and their biological activities in vitro and in vivo were evaluated. Compound 1q was screened out as the one with the best activity performance toward Xanthomonas axonopodis pv.
View Article and Find Full Text PDFMetabolomics
December 2024
School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, B15 2TT, UK.
Introduction: Tree bacterial diseases are a threat in forestry due to their increasing incidence and severity. Understanding tree defence mechanisms requires evaluating metabolic changes arising during infection. Metabolite extraction affects the chemical diversity of the samples and, therefore, the biological relevance of the data.
View Article and Find Full Text PDFDiscov Nano
December 2024
Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.
Cervical cancer remains a significant health challenge in developing countries are high due to low HPV vaccination rates, delayed diagnosis, and restricted healthcare access. Metal nanomaterials, such as copper oxide (CuO) nanoparticles (NPs), have shown significant promise in cancer therapy due to their ability to induce apoptosis. 5-Fluorouracil (5-Fu) enhances the cytotoxic effect against cervical cancer, working synergistically with CuO NPs to maximize the therapeutic impact while potentially reducing the 5-Fu's systemic side effects.
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