Unlabelled: The diagnostic accuracy of clinical-based body composition methods such as body mass index (BMI), waist circumference (WC), bioimpedance analysis (BIA), and dual energy X-ray absorptiometry (DXA) has yet to be evaluated in Hispanic adults. Moreover, it has also been suggested that previously established obesity cutoff values may need adjusting.
Purpose: The primary aim of this study was to investigate the diagnostic accuracy of BMI, WC, BIA, and DXA for obesity classification in Hispanic adults. The secondary aim was to internally derive obesity cutoff values producing equal sensitivity and specificity for the respective tests.
Methods: Hispanic females (n = 101) and males (n = 90) volunteered to participate in this study (18-45 years). Body fat percentage was estimated with BIA, DXA, and a 4-compartment (4C) model. Obesity-defined criteria was employed as follows: (Body fat percentage ≥ 25% and 35% and WC ≥ 102cm and 88cm for males and females, respectively; BMI ≥ 30 kg/m). A 4C model was used as a criterion to evaluate BMI, WC, DXA, and BIA.
Results: Sensitivity of DXA and BIA (74.1%-96.9%) was greater than BMI and WC (25.8%-51.9%) when using previously established standards. However, specificity was poor for DXA (<70%), but considered good to excellent for BMI, WC, and BIA (83.1%-96.6%) when using previously established standards. Internally derived cutoff values improved sensitivity for BMI and WC (74.2%-81.5%) and improved specificity for DXA (>80.0%).
Conclusion: The internally derived cutoff values, producing identical sensitivity, and specificity, were developed and shown to improve the diagnostic performance of the body composition methods compared to previously established obesity cutoff standards. Consequently, the internally derived obesity cutoff values are recommended for use by allied health professionals in clinical practice when equal sensitivity and specificity is desired.
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http://dx.doi.org/10.1016/j.jocd.2020.10.010 | DOI Listing |
J Formos Med Assoc
January 2025
Department of Medical Imaging and Radiology, National Taiwan University Hospital and College of Medicine, Taiwan; Center of Minimal-Invasive Interventional Radiology, National Taiwan University Hospital, Taipei, Taiwan; Hepatits Research Center, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Purpose: To investigate the association of skeletal muscle mass and quality with survival outcomes in patients with advanced hepatocellular carcinoma (HCC) treated with lenvatinib (LEN).
Methods: In this retrospective study, LEN-treated patients with HCC were enrolled. Sarcopenia and myosteatosis were evaluated on the basis of baseline skeletal muscle index and mean muscle attenuation, respectively, on computed tomography at the L3 level.
Medicine (Baltimore)
January 2025
Department of Clinical Nutrition, Tongde Hospital of Zhejiang Province, Hangzhou, China.
There are limited studies on the phase angle (PhA) and sarcopenic obesity (SO) in the Chinese population. This study aimed to establish 50 kHz-PhA reference data for SO population, and to evaluate the correlation between 50 kHz-PhA and SO. A total of 10,312 participants including 5415 men and 4897 women were enrolled in this study, and their resistance and reactance at 50 kHz, and body composition parameters were measured a segmental multifrequency bioelectrical impedance analysis device (InBody 720).
View Article and Find Full Text PDFJ Clin Transl Endocrinol
March 2025
Section on Growth and Obesity, Division of Intramural Research (DIR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.
Background: Identifying and treating metabolic syndrome (MetS) early is of great importance, as MetS portends numerous negative health outcomes. Identifying an inexpensive, readily available inflammatory biomarker that accurately predicts MetS could be of use to clinicians.
Methods: The aim of this study was to evaluate the relationship between the neutrophil-to-lymphocyte ratio (NLR) and MetS in U.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
July 2024
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041.
Although body mass index (BMI) is widely used as a simple tool to assess obesity, it has certain limitations and inaccuracies. It is known that visceral adipose tissue is closely related to cardiometabolic risks and all-cause mortality; however, precise measurement methods for visceral fat (magnetic resonance imaging and computed tomography) cannot be widely used. Thus, simple but accurate alternatives are valuable.
View Article and Find Full Text PDFF S Rep
December 2024
Northwell, New Hyde Park, New York.
Objective: To evaluate the characteristics of patients who exceeded the body mass index (BMI) threshold for fertility treatment at their initial visit and identify those for whom treatment would be constrained.
Design: Retrospective cohort study.
Setting: Academic medical center.
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