Recognizing aggressive movements is a challenging task in human activity recognition. Wearable smartwatch technology with machine learning may be a viable approach for human aggressive behavior classification. This research identified a viable classification model and feature selector (CM-FS) combination for separating aggressive from non-aggressive movements using smartwatch data and determined if only one smartwatch is sufficient for this task. A ranking method was used to select relevant CM-FS models across accuracy, sensitivity, specificity, precision, F-score, and Matthews correlation coefficient (MCC). The Waikato environment for knowledge analysis (WEKA) was used to run 6 machine learning classifiers (random forest, k-nearest neighbors (kNN), multilayer perceptron neural network (MP), support vector machine, naïve Bayes, decision tree) coupled with three feature selectors (ReliefF, InfoGain, Correlation). Microsoft Band 2 accelerometer and gyroscope data were collected during an activity circuit that included aggressive (punching, shoving, slapping, shaking) and non-aggressive (clapping hands, waving, handshaking, opening/closing a door, typing on a keyboard) tasks. A combination of kNN and ReliefF was the best CM-FS model for separating aggressive actions from non-aggressive actions, with 99.6% accuracy, 98.4% sensitivity, 99.8% specificity, 98.9% precision, 0.987 F-score, and 0.984 MCC. kNN and random forest classifiers, combined with any of the feature selectors, generated the top models. Models with naïve Bayes or support vector machines had poor performance for sensitivity, F-score, and MCC. Wearing the smartwatch on the dominant wrist produced the best single-watch results. The kNN and ReliefF combination demonstrated that this smartwatch-based approach is a viable solution for identifying aggressive behavior. This wrist-based wearable sensor approach could be used by care providers in settings where people suffer from dementia or mental health disorders, where random aggressive behaviors often occur.
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http://dx.doi.org/10.3390/s20216377 | DOI Listing |
Pathologica
December 2024
Department of Pharmacy, University of Salerno, Italy.
Objective: This study investigated metformin as a sensitizer for radiotherapy in oral squamous cell carcinoma (OSCC) to reduce the radiation intensity. It evaluated the drug's effect on Chromatin Assembly Factor-1 (CAF-1) expression, whose high levels correlate with worse prognosis of this cancer.
Methods: The effects of metformin, alone and with radiotherapy, were evaluated on CAL27 (HPV-) and SCC154 (HPV+) OSCC cells.
Sci Rep
January 2025
Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Double C-2 Like Domain Beta (DOC2B) located at 17q13.3 prevents metastasis by senescence induction and epithelial to mesenchymal transition inhibition in cervical cancer (CC). The extracellular vesicle (EV) mediated trafficking of DOC2B and its impact on tumor suppressive activity are not investigated in CC.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Pathology, Medical School of Nantong University, Nantong, China.
The progression of hepatoma is heavily influenced by the microenvironment. Tumor-associated macrophages (TAMs) are considered to play a critical role in the tumor microenvironment (TME) and increase the aggressiveness of hepatoma. The activation of hepatic stellate cells (HSCs) is involved in hepatoma progression, and accumulating evidence demonstrates a change in microRNA (miRNA) expression during HSC activation.
View Article and Find Full Text PDFSci Rep
December 2024
School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China.
Alpha-actin-1 (ACTN1) is a cytoskeletal protein, and new evidence suggests that it is associated with tumor progression and prognosis. However, the expression of ACTN1 in thyroid carcinoma (THCA) and its biological functions are not fully understood. This study aimed to explore the expression and biological function of ACTN1 in THCA.
View Article and Find Full Text PDFFront Immunol
December 2024
State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) of China, School of Pharmacy, Jinan University, Guangzhou, China.
Background: Stomach adenocarcinoma (STAD) is an aggressive malignancy characterized by high tumor plasticity and heterogeneity. This study investigates the role of Autophagy and Beclin 1 Regulator 1 (AMBRA1) in regulating tumor plasticity in STAD progression.
Methods: Combined with clinical data, the pan-cancer analysis of AMBRA1 was performed to analyze the role of AMBRA1 in STAD.
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