AI Article Synopsis
- This study examined the peak standardized uptake value (SUV) in SPECT-CT imaging to differentiate between chronic osteomyelitis, osteoradionecrosis, and medication-related osteonecrosis of the jaw (MRONJ).
- A total of 65 patients were assessed, revealing that chronic osteomyelitis had a significantly higher peak SUV compared to the other conditions.
- The findings suggest that peak SUV measurement can effectively aid in the evaluation and diagnosis of these jaw lesions.
Article Abstract
Introduction: Recently, standardized uptake value (SUV) has been applied for the evaluation of SPECT-CT. This study was performed to investigate the bone SPECT-CT peak SUV for chronic osteomyelitis, osteoradionecrosis and medication-related osteonecrosis of the jaw (MRONJ).
Methods: Sixty-five patients with jaw lesions (12 chronic osteomyelitis, 12 osteoradionecrosis and 41 MRONJ) underwent SPECT-CT after injection of technetium-99m hydroxymethylene diphosphonate. The peak SUV was compared for the chronic osteomyelitis with osteoradionecrosis and MRONJ using GI-BONE software. Statistical analyses for the peak SUV were performed by one-way repeated measures analysis of variance with Tukey's HSD test. A P-value lower than 0.05 was considered as statistically significant.
Results: Peak SUV for chronic osteomyelitis (15.6 ± 4.4) was significantly higher than those for osteoradionecrosis (6.7 ± 2.1, P = 0.000) and MRONJ (10.7 ± 6.1, P = 0.019).
Conclusion: The SPECT-CT peak SUV using GI-BONE software can be useful for the evaluation of jaw lesions, such as chronic osteomyelitis, osteoradionecrosis and MRONJ.
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| http://dx.doi.org/10.1111/1754-9485.13127 | DOI Listing |
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