Objective: The establishment of patient-centered measures capable of empirically determining meaningful cognitive change after surgery can significantly improve the medical care of epilepsy patients. Thus, this study aimed to develop reliable change indices (RCIs) and standardized regression-based (SRB) change norms for a comprehensive neuropsychological test battery in the German language.

Methods: Forty-seven consecutive patients with temporal lobe epilepsy underwent neuropsychological assessments, both before and 12 months after surgery. Practice-effect-adjusted RCIs and SRB change norms for each test score were computed. To assess their usefulness, the presented methods were applied to a clinical sample, and binary logistic regression analyses were conducted to model the odds of achieving improvement in quality of life (QOL) after surgery.

Results: The determined RCIs at 90% confidence intervals and the SRB equations for each test score included in the test battery are provided. Cohen's kappa analyses revealed a moderate mean agreement between the two measures, varying from slight to almost perfect agreement across test scores. Using these measures, a negative association between improvement in QOL and decline in verbal memory functions after surgery was detected (adjusted odds ratio = 0.09, = 0.006).

Significance: To the best of our knowledge, this study is the first to develop RCIs and SRB change norms necessary for the objective determination of neuropsychological change in a comprehensive test battery in the German language, facilitating the individual monitoring of improvement and decline in each patients' cognitive functioning and psychosocial situations after epilepsy surgery. The application of the described measures revealed a strong negative association between improvement in QOL and decline in verbal memory functions after surgery.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593256PMC
http://dx.doi.org/10.3389/fpsyg.2020.582836DOI Listing

Publication Analysis

Top Keywords

change norms
16
test battery
16
battery german
12
srb change
12
change
9
cognitive change
8
quality life
8
reliable change
8
change indices
8
standardized regression-based
8

Similar Publications

Purpose: Self-reported drinker identity, the extent to which one views oneself as a drinker, is associated with alcohol consumption and related harms in young adults. The current study examined changes in self-reported drinker identity, theoretically relevant factors associated with drinker identity development, and drinker identity's association with changes in drinking and alcohol-related consequences. We hypothesized that drinker identity would increase over time; theoretically relevant factors would be significantly and positively associated with that increase, and increases in drinking identity would be associated with elevated drinking and related consequences.

View Article and Find Full Text PDF

Split tendon transfer of the posterior tibialis for spastic equinovarus foot deformity: Does tendon routing impact post-operative ankle kinematics?

Gait Posture

January 2025

Department of Orthopaedics, BC Children's Hospital, 4500 Oak St, Vancouver, BC V6H 3N1, Canada; The Motion Lab, Sunny Hill Health Centre, 4480 Oak St, Vancouver, BC V6H 3N1, Canada; University of British Columbia, Faculty of Medicine, Department of Orthopaedics, 317 - 2194 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.

Background: Split tendon transfer of the posterior tibialis (SPOTT) is a surgical procedure in which the split posterior tibialis tendon is transferred posterior to the fibula (PO) with insertion on the peroneus brevis tendon to rebalance the forces across the hindfoot. Routing of the split tendon through the interosseous membrane (IO) is a variation with the potential benefit of augmenting ankle dorsiflexion in swing.

Research Question: Does IO routing improve ankle dorsiflexion in swing and/or varus in stance compared to PO routing?

Methods: A retrospective chart review was completed to identify forty-two patients who underwent a SPOTT procedure for equinovarus foot deformity.

View Article and Find Full Text PDF

Dating and relationship violence (DRV) among young people is widespread. DRV is associated with subsequent mental ill health, substance use and sexual risk among girls and boys and is a leading cause of morbidity and mortality among girls globally. Harmful social norms are widely recognised for their role in sustaining DRV, and interventions often seek to change these.

View Article and Find Full Text PDF

Introduction: Anthropology is the scientific exploration of the human body morphology. The present study aims to establish the anthropometric norms among young Persian ethnic women and compare them with golden proportion, a mathematical formula in facial esthetics.

Methods: This cross-sectional study was performed on Persian women between July 2020 and January 2021.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!