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| http://dx.doi.org/10.1590/0037-8682-0671-2020 | DOI Listing |
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Impact of the COVID-19 pandemic on lung cancer diagnosis in northern Poland-addressing the COVID-19 debt.
PLoS One
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Department of Water Resources, Climatology and Environmental Management, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Lung cancer, one of the leading causes of death due to neoplasms, requires prompt diagnosis and immediate treatment. The COVID-19 pandemic affected healthcare systems worldwide, having adverse effects on all aspects, particularly on the fate of patients with suspected neoplastic diseases. Limited access to healthcare, disruptions in regular operations (reassigning roles to some wards), postponed hospital admissions, prolonged diagnostic processes, and other factors have collectively led to the phenomenon known as COVID-19 debt.
View Article and Find Full Text PDFAnalysis of risk factors for benign central airway stenosis after COVID-19 infection.
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Henan Institute of Interconnected Intelligent Health, Henan Key Laboratory of Chronic Disease Prevention and Therapy & Intelligent Health Management, The First Affiliated Hospital of Zhengzhou University, Zhengzhou City, China.
Background: To investigate the risk factors associated with benign central airway stenosis following COVID-19 infection.
Methods: The clinical data of 235 patients hospitalized for COVID-19 infection at the First Affiliated Hospital of Zhengzhou University from October 2022 to October 2023 were retrospectively analyzed. Based on the occurrence of postoperative central airway stenosis, the patients were categorized into a stenosis group (118 cases) and a control group (117 cases).
Surveillance of public health pathogens in Lagos wastewater canals: a cross-sectional study.
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Center for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
Background: Wastewater-based epidemiology (WBE) is already being adopted for the surveillance of health conditions of communities and shows great potential for the monitoring of infectious pathogens of public health importance. There is however paucity of robust data to support extensive WBE in Nigeria. This study evaluated the prevalence of clinically relevant infectious pathogens and provided antimicrobial resistance profiles of bacteria pathogens in wastewater canals in Lagos State at a single point in time.
View Article and Find Full Text PDF6-aryloxy-2-aminopyrimidine-benzonitrile hybrids as anti-infective agents: Synthesis, bioevaluation, and molecular docking.
Arch Pharm (Weinheim)
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Fluoro & Agro Chemicals Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India.
This report explores the potential of novel 6-aryloxy-2-aminopyrimidine-benzonitrile scaffolds as promising anti-infective agents in the face of the increasing threat of infectious diseases. Starting from 2-amino-4,6-dichloropyrimidine, a series of 24 compounds inspired from the antiviral drugs dapivirine, etravirine, and rilpivirine were designed and synthesized via a two-step reaction sequence in good yields. Biological testing of synthetic analogs revealed potent inhibition against both viral and tuberculosis targets.
View Article and Find Full Text PDFThe Association of Smoking and SARS-CoV-2 Infection.
Tanaffos
January 2024
Chronic Respiratory Diseases Research Center (CRDRC), NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: SARS-CoV-2 is a member of the coronavirus family that has caused infections in humans. Iran, as one of the countries in West Asia, is facing a high prevalence of this virus. In this study, we aimed to investigate the association between smoking and COVID-19 outcomes during the pandemic and sociodemographic characteristics.
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