Topographic Differential Diagnosis of Chronic Plaque Psoriasis: Challenges and Tricks.

J Clin Med

Section of Dermatology and Venereology, Department of Medicine, University of Verona, 37129 Verona, Italy.

Published: November 2020

AI Article Synopsis

  • * The objective of the study was to identify and categorize other conditions that could be mistaken for plaque psoriasis based on the body's area affected, such as the scalp or trunk.
  • * Though diagnosing psoriasis is often clear-cut, it can occasionally be complex, necessitating tests like skin cultures or biopsies for accurate identification.

Article Abstract

Background: Psoriasis is an inflammatory skin disease presenting with erythematous and desquamative plaques with sharply demarcated margins, usually localized on extensor surface areas.

Objective: To describe the common differential diagnosis of plaque psoriasis classified according to its topography in the scalp, trunk, extremities, folds (i.e., inverse), genital, palmoplantar, nail, and erythrodermic psoriasis.

Methods: A narrative review based on an electronic database was performed including reviews and original articles published until 1 September 2020, assessing the clinical presentations and differential diagnosis for psoriasis.

Results: Several differential diagnoses could be considered with other inflammatory, infectious, and/or neoplastic disorders. Topographical differential diagnosis may include seborrheic dermatitis, tinea capitis, lichen planopilaris in the scalp; lupus erythematosus, dermatomyositis, cutaneous T-cell lymphomas, atopic dermatitis, syphilis, tinea corporis, pityriasis rubra pilaris in the trunk and arms; infectious intertrigo in the inguinal and intergluteal folds and eczema and palmoplantar keratoderma in the palms and soles.

Conclusions: Diagnosis of psoriasis is usually straightforward but may at times be difficult and challenging. Skin cultures for dermatophytes and/or skin biopsy for histological examination could be required for diagnostic confirmation of plaque psoriasis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695211PMC
http://dx.doi.org/10.3390/jcm9113594DOI Listing

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