East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral anticoagulants are commonly used in current daily practice, the unique risk-benefit trade-off in East Asians has been a topic of emerging interest. In this article, we propose updated evidence and future directions of antithrombotic treatment in East Asian patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-0040-1718729 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recent changes in ENSO's impacts on the summertime circumglobal teleconnection and mid-latitude extremes.
Nat Commun
January 2025
School of Atmospheric Sciences, Sun Yat-Sen University, and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
The boreal summer circumglobal teleconnection (CGT) provides a primary predictability source for mid-latitude Northern Hemisphere climate anomalies and extreme events. Here, we show that the CGT's circulation structure has been displaced westward by half a wavelength since the late 1970s, more severely impacting heatwaves and droughts over East Europe, East Asia, and southwestern North America. We present empirical and modelling evidence of the essential role of El Niño-Southern Oscillation (ENSO) in shaping this change.
View Article and Find Full Text PDFChinese Visceral Adiposity Index Trajectory and Stroke in Prediabetes and Diabetes: A Prospective Cohort Study.
Diabetes Metab Res Rev
January 2025
Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention, Department of Biostatistics and Epidemiology, Ministry of Education, School of Public Health, China Medical University, Shenyang, China.
Aims: Stroke is a common diabetic complication, by which the Chinese visceral adiposity index (CVAI) is confirmed as a better predictor of visceral fat. However, the relationship between CVAI change and the stroke risk among patients with diabetes and prediabetes remains unclear. Therefore, we aimed to examine the association of CVAI trajectory with the risk of stroke.
View Article and Find Full Text PDFand gene variants affecting clopidogrel metabolism in a South Asian population from Sri Lanka.
Pharmacogenomics
January 2025
Department of Anatomy, Genetics and Biomedical Informatics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Aims: Clopidogrel exhibits substantial variability in therapeutic response, largely contributed by genetic factors. The pharmacogenomic variants data on clopidogrel metabolism in South Asians have been sparsely studied. This study explores the impact of and gene variants on clopidogrel metabolism in Sri Lankans, revealing significant pharmacogenomic insights with broader implications for South Asians.
View Article and Find Full Text PDFOptimal BMI cutoff for lean MASLD/MetALD and adverse hepatic outcomes in East-Asian populations.
Eur J Intern Med
January 2025
Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea; Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea; Institute for Innovation in Digital Healthcare, Yonsei University Health System, South Korea. Electronic address:
Urinary calculi successfully expelled in a patient through traditional Chinese exercise: A case report.
Medicine (Baltimore)
November 2024
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Rationale: Urinary calculi are hard mineral deposits that typically require medication or surgery, such as lithotripsy. This case report presents traditional Chinese exercises (TCEs) as a potential alternative for stone expulsion.
Patient Concerns: A 41-year-old male with no history of urinary tract stones, experienced sudden severe lower back and abdominal pain accompanied by nausea and vomiting.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!