Can Genomic Sequencing Identify High-Risk Barrett's Esophagus Earlier Than Pathologists?

Cancer Cell

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA; Eli and Edythe L. Broad Institute, Cambridge, MA, USA. Electronic address:

Published: November 2020

Barrett's esophagus (BE) is a precursor to esophageal adenocarinoma, and screening for cancer risk focuses upon histologic assessment of dysplasia within endoscopic biopsies. A recent study in Nature Medicine contributes to growing evidence that genomic assessment of non-dysplastic BE samples can identify patients at greatest risk of progressing to cancer.

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http://dx.doi.org/10.1016/j.ccell.2020.10.020DOI Listing

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