Through vehicle-to-vehicle (V2V) communication, both human-driven and autonomous vehicles can actively exchange data, such as velocities and bumper-to-bumper distances. Employing the shared data, control laws with improved performance can be designed for connected and autonomous vehicles (CAVs). In this article, taking into account human-vehicle interaction and heterogeneous driver behavior, an adaptive optimal control design method is proposed for a platoon mixed with multiple preceding human-driven vehicles and one CAV at the tail. It is shown that by using reinforcement learning and adaptive dynamic programming techniques, a near-optimal controller can be learned from real-time data for the CAV with V2V communications, but without the precise knowledge of the accurate car-following parameters of any driver in the platoon. The proposed method allows the CAV controller to adapt to different platoon dynamics caused by the unknown and heterogeneous driver-dependent parameters. To improve the safety performance during the learning process, our off-policy learning algorithm can leverage both the historical data and the data collected in real time, which leads to considerably reduced learning time duration. The effectiveness and efficiency of our proposed method is demonstrated by rigorous proofs and microscopic traffic simulations.
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http://dx.doi.org/10.1109/TCYB.2020.3029077 | DOI Listing |
Transl Vis Sci Technol
January 2025
Vrije Universiteit Amsterdam, Department of Human Movement Sciences, Amsterdam Movement Sciences and Institute Brain and Behaviour Amsterdam (iBBA), Amsterdam, the Netherlands.
Purpose: Understanding the impact of vision impairment on dynamic tasks requiring visual processing is crucial for developing effective adaptive strategies that support individuals with vision impairment in optimizing their performance in natural tasks. This study aimed to establish the gaze patterns used by individuals with vision impairment when hitting a moving target.
Methods: Nineteen tennis players with vision impairment were recruited and their eye and head movements were tracked while they returned tennis serves.
Appl Environ Microbiol
December 2024
Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
is an obligate anaerobic, Gram-positive bacterium that produces toxins. Despite technological progress, conducting gene expression analysis of under different conditions continues to be labor-intensive. Therefore, there is a demand for simplified tools to investigate the transcriptional and translational regulation of .
View Article and Find Full Text PDFImmunol Rev
December 2024
Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
αβT cells protect vertebrates against many diseases, optimizing surveillance using mechanical force to distinguish between pathophysiologic cellular alterations and normal self-constituents. The multi-subunit αβT-cell receptor (TCR) operates outside of thermal equilibrium, harvesting energy via physical forces generated by T-cell motility and actin-myosin machinery. When a peptide-bound major histocompatibility complex molecule (pMHC) on an antigen presenting cell is ligated, the αβTCR on the T cell leverages force to form a catch bond, prolonging bond lifetime, and enhancing antigen discrimination.
View Article and Find Full Text PDFJ Virol
December 2024
College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, Beijing, China.
Unlabelled: Quorum sensing (QS) can regulate diverse critical phenotypic responses in (), enabling bacterial adaptation to external environmental fluctuations and optimizing population advantages. While there is emerging evidence of QS's involvement in influencing phage infections, our current understanding remains limited, necessitating further investigation. In this study, we isolated and characterized a novel phage designated as BUCT640 that infected PAO1.
View Article and Find Full Text PDFFront Bioeng Biotechnol
December 2024
School of Aeronautic Science and Engineering, Beihang University, Beijing, China.
Introduction: In-stent restenosis remains a significant challenge in coronary artery interventions. This study aims to explore the relationship between exercise intensity and stent design, focusing on the coupled response of the stent structure and hemodynamics at different exercise intensities.
Methods: A coupled balloon-stent-plaque-artery model and a fluid domain model reflecting structural deformation were developed to investigate the interaction between coronary stents and stenotic vessels, as well as their impact on hemodynamics.
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