AI Article Synopsis
- The study aimed to investigate the occurrence of refeeding syndrome in healthy children under 3 years old admitted for failure to thrive (FTT).
- Out of 179 eligible patients, none showed laboratory signs of refeeding syndrome, with 81% having initial lab tests and 39% undergoing follow-up tests after admission.
- The findings suggest that routine lab monitoring for electrolyte issues in these patients may not be necessary, indicating a need for more detailed research to improve clinical practices and reduce unnecessary testing.
Article Abstract
Objectives: To determine the incidence of refeeding syndrome in otherwise healthy children <3 years of age admitted for failure to thrive (FTT).
Methods: A multicenter retrospective cohort study was performed on patients aged ≤36 months admitted with a primary diagnosis of FTT from January 1, 2011, to December 31, 2016. The primary outcome measure was the percentage of patients with laboratory evidence of refeeding syndrome. Exclusion criteria included admission to an ICU, parenteral nutrition, history of prematurity, gastrostomy tube feeds, and any complex chronic conditions.
Results: Of the 179 patients meeting inclusion criteria, none had laboratory evidence of refeeding syndrome. Of these, 145 (81%) had laboratory work done at the time of admission, and 69 (39%) had laboratory work repeated after admission. A small percentage (6%) of included patients experienced an adverse event due to repeat laboratory draw.
Conclusions: In otherwise healthy hospitalized patients <3 years of age with a primary diagnosis of FTT, routine laboratory monitoring for electrolyte derangements did not reveal any cases of refeeding syndrome. More robust studies are needed to determine the safety and feasibility of applying low-risk guidelines to this patient population to reduce practice variability and eliminate unnecessary laboratory evaluation and monitoring.
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| http://dx.doi.org/10.1542/hpeds.2020-0124 | DOI Listing |
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