[Research progress on mechanisms of traditional Chinese medicine in prevention and treatment of postoperative peritoneal adhesion].

Zhongguo Zhong Yao Za Zhi

School of Life Science and Engineering, Southwest Jiaotong University Chengdu 610031, China Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

Published: September 2020

AI Article Synopsis

  • Peritoneal adhesion is a common complication following abdominal surgery that can significantly impact patients' quality of life, despite advancements in surgical techniques reducing its incidence.
  • Current treatments fall short due to the absence of specialized drugs, highlighting a gap in effective therapeutic options.
  • Traditional Chinese medicine (TCM) shows promising potential in treating peritoneal adhesion, but research and product development in this area remain under-explored, limiting progress in the field; this paper aims to provide a thorough overview of TCM's efficacy and mechanisms to support further investigation and commercialization.

Article Abstract

Peritoneal adhesion is one of the common complications after abdominal operation, which could seriously affect the quality of life in patients. Although the development of modern surgical technology and the improvement of doctors' operation level have reduced the incidence of peritoneal adhesion to a certain extent, due to the lack of special treatment drugs, the therapeutic effect still cannot meet the expectations and requirements of clinicians and patients. Traditional Chinese medicines(TCM) have unique advantages and remarkable curative effect in the treatment of peritoneal adhesion, and they can play an important role in regulating multiple pathological links. However, the relevant researches and product development of TCM against peritoneal adhesion have not attracted enough attention from industry scholars. As for the related work that has been carried out, most of the studies on the efficacy and mechanism are not thorough and systematic enough, seriously restricting the industrial development in this field. In this paper, the efficacy and mechanism were systematically described and summarized based on the review of papers in the recent years, so as to provide a reference for the thorough study of TCM in the prevention and treatment of peritoneal adhesions, and promote the deep development and industrialization process of related products.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20200609.601DOI Listing

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