Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care. | LitMetric

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Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care. | LitMetric

Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care.

Klara M Posfay-Barbe Diego O Andrey Julien Virzi Patrick Cohen Fiona Pigny Ana R Goncalves Selina Pinosch Laurence Lacroix Silvia Stringhini Laurent Kaiser Nicolas Vuilleumier Arnaud G L'Huillier

Clin Infect Dis

Department of Woman, Child, and Adolescent Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.

Published: April 2021

* This rate is over 100 times higher than the number of pediatric cases confirmed through RT-PCR testing.
* The MEDsan IgG rapid diagnostic test showed accurate results when compared to the combined ELISA and immunofluorescence standard testing methods.

In 208 children seeking medical care, the seropositivity rate of anti-SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR-confirmed pediatric cases. Compared with the gold-standard combined ELISA + immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717220	PMC
http://dx.doi.org/10.1093/cid/ciaa1702	DOI Listing

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