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Polymicrobial empyema in a patient with lung adenocarcinomacontaining .
BMJ Case Rep
January 2025
Thoracic Medicine and Surgery, Temple University Hospital, Philadelphia, Pennsylvania, USA.
A man in his 60s with advanced COPD and lung adenocarcinoma presented with sepsis and acute hypoxaemic respiratory failure. Imaging revealed bilateral pleural effusions, and he was found to have a polymicrobial empyema which included Despite appropriate treatment, he continued to deteriorate and ultimately died of sepsis. species, typically benign constituents of the oral microbiota, rarely can instigate pleuropulmonary infections, especially in immunocompromised individuals.
View Article and Find Full Text PDFLongitudinal profiles of oral microbiome in patients with nasopharyngeal carcinoma and their prognostic implications.
J Oral Microbiol
January 2025
State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Background: Oral microbiome has been associated with various cancers, including nasopharyngeal carcinoma (NPC), but its role in cancer treatment and prognosis remains largely unknown. This study aims to address the dynamic changes in oral microbiome following cancer treatment and their prognostic implications in NPC patients.
Patients And Methods: Unstimulated whole saliva samples were collected from 23 NPC patients before and after treatment, with an average of 2.
Relationship Between the Presence of Red Complex Species and the Distribution of Other Oral Bacteria, Including Major Periodontal Pathogens in Older Japanese Individuals.
Int J Mol Sci
November 2024
Department of Pediatric Dentistry, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima 734-8553, Japan.
Article Synopsis
- Red complex bacteria are highly virulent in periodontal disease, and this study focused on their relationships with other oral bacteria in older Japanese individuals.
- Polymerase chain reaction was used to analyze dental plaque from 116 subjects, finding that individuals positive for red complex bacteria had significantly higher detection rates of certain periodontal pathogens compared to those who were negative.
- The findings indicate that individuals harboring all three red complex species have a unique oral microbiome, showcasing greater α-diversity and lower β-diversity, suggesting they may be more prone to developing periodontal disease.
Impact of Malocclusions on Periodontopathogenic Bacterial Load and Progression of Periodontal Disease: A Quantitative Analysis.
Microorganisms
July 2024
Department of Orthodontics and Dentofacial Orthopaedics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
(1) Periodontal disease (PD) is a globally prevalent chronic inflammatory condition, exacerbated by the dysbiosis of the oral microbiota. This study aims to evaluate the bacterial load of specific periodontopathogenic bacteria in patients with malocclusions (MAL) compared to those without. (2) Methods: Conducted at the "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania, this pilot study involved two groups: patients with MAL and PD, and patients with PD but without MAL.
View Article and Find Full Text PDFPrevalence of species of yellow, purple and green microbial complexes in endo-perio lesions: a systematic review.
Braz Oral Res
June 2024
Universidade Federal de Santa Catarina - UFSC, Department of Dentistry, Florianopolis, SC, Brazil.
This review aimed to determine the prevalence of species of yellow, purple and green microbial complexes in root canals (RC) and periodontal pockets (PP) of teeth with endodontic-periodontal lesions. For this purpose, two reviewers searched the literature up to January 2022. Studies reporting the prevalence of species of the yellow, purple and green microbial complexes in teeth diagnosed with endodontic-periodontal lesions were included.
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