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'It's Not Written All Over My Face': Constructing Chronic Pain as Invisible in Pain Clinic Consultations and Interviews.
Clin J Pain
January 2025
Associate professor, University of Antwerp.
Objectives: Historically in medicine and beyond, the understanding of and treatment of pain is based on finding tissue injury. The fact that for chronic pain, there often is no (longer) any traceable tissue injury, in combination with the fact that pain essentially is a private experience, poses a challenge for clinical communication. This paper therefore examines how pain is linguistically and interactionally constructed as invisible.
View Article and Find Full Text PDFEnabling electric field model of microscopically realistic brain.
Brain Stimul
December 2024
Department of Electrical and Computer Eng., Worcester Polytechnic Inst., Worcester, MA, USA; Department of Mathematical Sciences, Worcester Polytechnic Inst., Worcester, MA, USA.
Background: Modeling brain stimulation at the microscopic scale may reveal new paradigms for various stimulation modalities.
Objective: We present the largest map to date of extracellular electric field distributions within a layer L2/L3 mouse primary visual cortex brain sample. This was enabled by the automated analysis of serial section electron microscopy images with improved handling of image defects, covering a volume of 250 × 140 × 90 μm³.
The double invisibility of Long Covid in children.
Soc Sci Med
April 2024
Nuffield Department of Primary Care Health Sciences, University of Oxford, OX2 6GG, UK. Electronic address:
The Covid-19 pandemic has been dominated by discussions of mild and short-lasting cases or acutely serious or lethal forms of the disease; less attention has been paid to long-term Covid-19 symptoms ('Long Covid'), particularly in children. This analysis of the experiences of children and adolescents with Long Covid, and those of their parents/caregivers, argues that children with Long Covid encounter a 'double invisibility' due to the condition's limited social currency and their status as the youngest members of society. We draw on 39 narrative interviews about children's and adolescents' experiences, conducted in 2021-2022 in the United Kingdom.
View Article and Find Full Text PDFTargeting of tumor cells by custom antigen transfer: a novel approach for immunotherapy of cancer.
Front Oncol
October 2023
Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Firenze, Italy.
In the early stages of carcinogenesis, the transformed cells become "invisible" to the immune system. From this moment on, the evolution of the tumor depends essentially on the genotype of the primitive cancer cells and their subsequent genetic drift. The role of the immune system in blocking tumor progression from the earliest stages is largely underestimated because by the time tumors are clinically detectable, the immune system has already completely failed its task.
View Article and Find Full Text PDFClock genes regulate skeletal muscle energy metabolism through NAMPT/NAD/SIRT1 following heavy-load exercise.
Am J Physiol Regul Integr Comp Physiol
November 2023
Institute of Sports Medicine and Health, Chengdu Sport University, Chengdu, China.
The biological clock is an invisible "clock" in the organism, which can regulate behavior, physiology, and biochemical reactions. However, the relationship between clock genes and energy metabolism in postexercise skeletal muscle is not well known. The purpose of this study was to determine the mechanisms through which peripheral clock genes regulate energy metabolism in skeletal muscle.
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