Quinone-Based Drugs: An Important Class of Molecules in Medicinal Chemistry.

Med Chem

Universidade Federal Fluminense, Instituto de Quimica, Departamento de Quimica Organica, Campus do Valonguinho, Niterói, 24020-150, RJ, Brazil.

Published: January 2022

Background: Several quinones are on the pharmaceutical market as drugs for the treatment of several diseases.

Objective: The aim of this review was to provide an overview of the quinones that have become drugs for several therapeutic applications.

Methods: We have comprehensively and critically discussed all the information available in the literature about quinone-based drugs.

Results: In this review, the various aspects of the chemistry and biochemistry of these drugs are highlighted, including their repositioning, drug combination and their new uses.

Conclusion: A number of studies related to quinone drugs for different pharmaceutical uses show that the interest in new applications is still increasing in recent years.

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Source
http://dx.doi.org/10.2174/1573406416666201106104756DOI Listing

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