Ichthyosis uterus is an uncommon condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. This condition most commonly develops secondary to longstanding cervical obstruction or chronic inflammation. It is considered a benign lesion, but its association with endometrial malignancy has been reported in the literature. We are reporting a case of ichthyosis uteri with dysplasia associated with cervical intraepithelial neoplasm (CIN III). The case is reported for its rarity and to aware about neoplastic potential of ichthyosis uteri.
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Ichthyosis uteri complicated by endometrial adenocarcinoma with transitional cell differentiation: A case report.
Medicine (Baltimore)
July 2024
Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310000, China.
Rationale: Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare.
Patient Concerns: A 68-year-old woman has been experiencing sporadic, minor vaginal hemorrhages for a few months.
[Dysplastic ichthyosis uteri-like changes of the entire endometrium associated with a high-grade squamous intraepithelial lesion of the uterine cervix: report of a case].
Zhonghua Bing Li Xue Za Zhi
September 2023
QuanZhou Women's and Children's Hospital, Quanzhou 362000, China.
Ichthyosis uteri: A keratinizing squamous metaplasia of the endometrium with premalignant potential.
Gynecol Oncol Rep
April 2023
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA.
•Ichthyosis uteri is a rare condition describing extensive endometrial keratinization.•There may be an association with squamous cell carcinoma of the endometrium.•Endometrial extension of cervical malignancy may closely resemble ichthyosis.
View Article and Find Full Text PDFIchthyosis uteri associated with squamous cell carcinoma of the endometrium - a case report.
Acta Chir Belg
December 2023
Department of Pathology, University Hospital for Tumours, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.
Background: Ichthyosis uteri is an extremely rare condition in which the entire or extensive parts of endometrial lining are replaced by stratified squamous epithelium. Malignant potential of this entity is unclear and its association with dysplastic changes and primary squamous cell carcinoma of the endometrium and endometrial adenocarcinoma has been reported. However, lack of data makes difficult to interpret the significance of neoplasms arising from this condition.
View Article and Find Full Text PDFCarcinoma Cervix Leading to Ichthyosis Uteri: A Rare Case Report.
J Obstet Gynaecol India
October 2021
P.C. Sethi Hospital, 5/5 , Yeshwant Niwas Road, Rani Sati Colony, Indore, M.P India.
Unlabelled: Ichthyosis uteri is an exceedingly rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. It is a benign lesion and its association with benign and malignant conditions has been reported in the literature (Bewtra, Xie, Hunter, Jurgensen (Arch Pathol Lab Med 29:e124-e125, 2005)). Originally described as an endometrial response to iatrogenically introduced caustic substances, similar changes have since been described in association with a variety of inflammatory conditions of the endometrium.
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