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Primary Central Nervous System Vasculitis (PCNSV): A Case Report Emphasizing Diagnostic Precision and Therapeutic Approaches.
Cureus
November 2024
Department of Diagnostic Radiology and Nuclear Medicine, Graduate School of Medicine, Gunma University, Maebashi, JPN.
This report presents a case of primary central nervous system vasculitis (PCNSV), emphasizing the need for precise diagnosis and individualized treatment. PCNSV is a rare inflammatory condition confined to the central nervous system (CNS) that affects small- to medium-sized vessels and can cause severe neurological damage if left untreated. A 73-year-old woman with no previous medical history presented with rapidly progressive right-sided hemiparesis and cognitive impairment.
View Article and Find Full Text PDFLong-Term Carotid Plaque Progression and the Role of Intraplaque Hemorrhage: Analysis from Deep Learning-based Longitudinal Vessel Wall Imaging.
medRxiv
December 2024
Department of Bioengineering, University of Washington, Seattle, WA, USA.
Background: Carotid atherosclerosis is a major etiology of stroke. Although intraplaque hemorrhage (IPH) is known to increase stroke risk and plaque burden, its long-term effects on plaque dynamics remain unclear.
Objectives: This study aimed to evaluate the long-term impact of IPH on carotid plaque burden progression using deep learning-based segmentation on multi-contrast vessel wall imaging (VWI).
Atherosclerotic plaque evolution predicts cerebral ischemic events in patients with intracranial atherosclerosis: a multicentre longitudinal study using high-resolution MRI.
Eur Radiol
December 2024
Department of Neurology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Background: Intracranial atherosclerosis (ICAS) is the leading cause of ischemic stroke in Asians and the recurrent rate remains high despite the optimal medical treatment. This study aimed to confirm that follow-up high-resolution magnetic resonance imaging (hrMRI) provided essential values in predicting subsequent cerebral ischemic events in patients with ICAS.
Methods: Patients with moderate to severe stenosis in the middle cerebral artery (MCA) defined by magnetic resonance (MRA) or computed tomography angiography (CTA) were recruited from three centers retrospectively.
Rete anomaly of the middle cerebral artery: case series of 13 patients from the Northeastern United States.
J Neurointerv Surg
December 2024
Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.
Background: Rete middle cerebral artery (MCA) is a rare anomaly of the intracranial circulation that mimics congenital Moyamoya disease (MMD). Similar to MMD, it is reported almost exclusively in East-Asian ethnicities. Here, we report 13 patients with rete MCA anomaly from a predominantly non-Asian background in the USA.
View Article and Find Full Text PDF7T MRI as a powerful tool to detect small and medium size vessel CNS vasculitis.
AJNR Am J Neuroradiol
December 2024
Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland (A.H., W.A., A.B.,R.W., P.R.), Department of Neuroradiology, Kantonsspital Aarau, Aarau, Switzerland (P.M.), Department of Neurology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland (D.J.S.,M.G., M.R.H.), Institute of Radiology, Clinic Maennedorf, Maennedorf, Zurich, Switzerland (E.J.), Department of Neurology, RHNe, Hôpital Pourtalès, Neuchâtel, Switzerland (P.M.), Department of Rheumatology, Inselspital, University of Bern, Bern, Switzerland (L.C.) Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland (R.W., P.R.).
Imaging can help to diagnose CNS vasculitis. Yet so far, no imaging studies of CNS vasculitis at 7T are available. We share our experience of vessel wall imaging (VWI) at 7T in patients with suspected vasculitis.
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