A case is presented of a woman with a history of daily persistent head pressure and dizziness who developed a cytotoxic lesion of the splenium of the corpus callosum after an acute withdrawal of chronic acetazolamide treatment and then, in quick succession, a CSF pressure/volume drop with a lumbar puncture. This is the first documentation that rapid alterations of CSF pressure/volume may trigger cytotoxic lesions in the central nervous system.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603566 | PMC |
| http://dx.doi.org/10.1155/2020/8849645 | DOI Listing |
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