AI Article Synopsis
- * Six racehorses were tested under three scenarios: regular exercise, exercise after furosemide treatment, and exercise after blood removal followed by reinfusion.
- * Results showed that fluid volumes in the body compartments remained stable during regular exercise but decreased significantly after furosemide, while blood reinfusion improved total body water and intracellular fluid levels.
Article Abstract
High pulmonary blood pressure contributes to exercise-induced pulmonary hemorrhage. The objective of this study was to use bioimpedance spectroscopy to assess body fluid compartment volumes under 3 conditions in 6 racehorses: i) Pre- and post-supramaximal treadmill exercise (control); ii) Exercise 4 hours after furosemide (0.5 mg/kg body weight, IV); iii) Exercise, removal of ~14 L of blood and subsequent reinfusion of the blood. Statistical analysis used linear mixed effects models. Body compartment volumes did not change during the control runs. Total body water (TBW) ( = 0.007, = 0.007), extracellular fluid (ECF) ( = 0.003, = 0.003), and intracellular fluid (ICF) volumes ( = 0.04, = 0.04) decreased pre- and post-exercise following furosemide administration. The ICF trended to decrease ( = 0.07) after slow removal of blood. Blood reinfusion increased TBW ( = 0.02, = 0.02) and ICF ( = 0.005, = 0.005) pre- and post-exercise.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560766 | PMC |
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