Metagenome Proteins and Database Contamination.

mSphere

Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts, USA

Published: November 2020

Continued influx of metagenome-derived proteins with misannotated taxonomy into conventional databases, including RefSeq, threatens to eliminate the value of taxonomy identifiers. To prevent this, urgent efforts should be undertaken by submitters of metagenomic data sets as well as by database managers.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643828PMC
http://dx.doi.org/10.1128/mSphere.00854-20DOI Listing

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