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| http://dx.doi.org/10.1093/cvr/cvaa315 | DOI Listing |
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Microrheometric study of damage and rupture of capsules in simple shear flow.
J Fluid Mech
December 2024
Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering, Compiégne, France.
Capsules, which are potentially-active fluid droplets enclosed in a thin elastic membrane, experience large deformations when placed in suspension. The induced fluid-structure interaction stresses can potentially lead to rupture of the capsule membrane. While numerous experimental studies have focused on the rheological behavior of capsules until rupture, there remains a gap in understanding the evolution of their mechanical properties and the underlying mechanisms of damage and breakup under flow.
View Article and Find Full Text PDFReversible Thixotropic Rheological Properties of Graphene-Incorporated Epoxy Inks for Self-Standing 3D Printing.
ACS Macro Lett
January 2025
Department of Energy Science, Sungkyunkwan University, Suwon 16419, Republic of Korea.
As three-dimensional (3D) printing has emerged as a new manufacturing technology, the demand for high-performance 3D printable materials has increased to ensure broad applicability in various load-bearing structures. In particular, the thixotropic properties of materials, which allow them to flow under applied external forces but resist flowing otherwise, have been reported to enable rapid and high-resolution printing owing to their self-standing and easily processable characteristics. In this context, graphene nanosheets exhibit unique π-π stacking interactions between neighboring sheets, likely imparting self-standing capability to low-viscosity inks.
View Article and Find Full Text PDFQuantitative investigation of a 3D bubble trapper in a high shear stress microfluidic chip using computational fluid dynamics and L*A*B* color space.
Biomed Microdevices
January 2025
Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 111 Suwannabhumi Canal Rd, Bang Pla, Bang Phli District, Samut Prakan, 10540, Thailand.
Microfluidic chips often face challenges related to the formation and accumulation of air bubbles, which can hinder their performance. This study investigated a bubble trapping mechanism integrated into microfluidic chip to address this issue. Microfluidic chip design includes a high shear stress section of fluid flow that can generate up to 2.
View Article and Find Full Text PDFEffect of plaque micro-watershed changes on carotid atherosclerosis.
Comput Methods Programs Biomed
January 2025
Dalian University of Technology Affiliated Central Hospital, Dalian 116024, China.
Objective: The study aims to elucidate the mechanisms underlying plaque growth by analyzing the variations in hemodynamic parameters within the plaque region of patients' carotid arteries before and after the development of atherosclerotic lesions.
Methods: The study enrolls 25 patients with common carotid artery stenosis and 25 with tandem carotid artery stenosis. Based on pathological analysis, three-dimensional models of the actual blood vessels before and after the lesion are constructed for two patients within a two-year period.
Shear-induced rotation enhances protein adsorption.
Colloids Surf B Biointerfaces
January 2025
State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Jilin, Changchun 130022, PR China; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, PR China. Electronic address:
Theories predicted that shear promotes desorption, but due to the presence of factors such as aggregation effects, it is difficult to observe how shear influences the adsorption and desorption of individual protein molecules. In this study, we employed high-throughput single-molecule tracking and molecular dynamics simulations to investigate how shear flow affects the adsorption kinetics of plasma proteins (including human serum albumin, immunoglobulin G, and fibrinogen) at solid-liquid interfaces. Over the studied shear rate range of 0 - 10 s, shear stress did not trigger the protein desorption.
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