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Flexible Nasal Tip Produced by Slender Septal Extension Graft.
Aesthetic Plast Surg
August 2024
Chiu Plastic Surgery Clinic, 9th floor, KBL center, 110, Dosan-daero, Gangnam-gu, Seoul, Republic of Korea.
Septal extension grafts (SEGs) can increase projection. However, it requires a large amount of graft and can result in a frozen tip. Thus, this study introduces a modified SEG, called a partial SEG.
View Article and Find Full Text PDFUsing nominal group technique to identify perceived barriers and facilitators to improving uptake of the Prison Needle Exchange Program in Canadian federal prisons by correctional officers and healthcare workers.
Int J Drug Policy
August 2024
Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine. 135 College St., Suite 323, New Haven, CT 06510, USA; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, USA; Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Background: Elimination of bloodborne viruses including HIV and hepatitis C virus from prisons requires high coverage of evidence-based interventions that prevent bloodborne virus transmission, including needle and syringe programs. Canada launched a Prison Needle Exchange Program (PNEP) in nine federal prisons in 2018; however, uptake among people who inject drugs in prison remains low. We aimed to explore barriers and facilitators to improving PNEP uptake identified by correctional officers and healthcare workers.
View Article and Find Full Text PDFEpigenetic editing for autosomal dominant neurological disorders.
Front Genome Ed
March 2024
Neurology Department, Stem Cell Program and Gene Therapy Center, MIND Institute, UC Davis Health System, Sacramento, CA, United States.
Article Synopsis
- - Epigenetics involves changes in gene expression without altering the DNA sequence, influencing cell differentiation and maintaining gene activity during cell division.
- - These modifications impact how tightly DNA wraps around histones, with tighter wrapping creating a state called heterochromatin, which silences gene expression.
- - Researchers are exploring ways to use natural epigenetic processes to create proteins that regulate gene expression, offering potential treatments for genetic disorders by modifying the body's existing gene expression.
Comparison of the effectiveness of two manual toothbrushes: Conventional design versus double-sided toothbrush design. A pilot study.
Int J Dent Hyg
May 2024
Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Madrid, Spain.
Objectives: Dental hygiene is the most effective method in the prevention of oral diseases. However, most patients do not use the recommended teeth brushing techniques and/or time brushing is insufficient. With this objective, modifications in conventional toothbrushes have been developed to deal with these findings.
View Article and Find Full Text PDFFlat mount preparation for whole-mount fluorescent imaging of zebrafish embryos.
Biol Open
July 2023
Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
The zebrafish is a widely used model organism for biomedical research due to its ease of maintenance, external fertilization of embryos, rapid embryonic development, and availability of established genetic tools. One notable advantage of using zebrafish is the transparency of the embryos, which enables high-resolution imaging of specific cells, tissues, and structures through the use of transgenic and knock-in lines. However, as the embryo develops, multiple layers of tissue wrap around the lipid-enriched yolk, which can create a challenge to image tissues located deep within the embryo.
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