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A Dual-Pathway Responsive Mechanophore for Intelligent Luminescent Polymer Materials.

J Am Chem Soc

January 2025

Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou 310058, PR China.

Mechanoluminescent units, when integrated into polymer matrices, undergo structural transformations in response to mechanical force, resulting in changes in fluorescence. This phenomenon holds considerable promise for the development of stress-sensing materials. Despite the high demand for robust, tunable mechanoluminescent mechanophores for force assessment and smart force-responsive materials, strategies for their design and synthesis remain underdeveloped.

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The present study summarises recent developments in solar-assisted extraction systems for distillation of essential oil from aromatic and medicinal plants. Various solar integrated essential oil extraction systems are compared based on performance parameters such as essential oil yield and system efficiency along with their potential effects on the domains of renewable energy. Solar steam distillation is an environmentally beneficial and energy-efficient technology of desalination that is especially ideal for areas with plentiful sun resources.

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Anthropogenic activities such as industrial pollution of water bodies possess threat to floras leading to extinction and endangerment. This study investigates the impact of industrial pollution on vegetation along River Chenab and its associated drains. Rivers and channels transporting industrial effluents have been determined to be significantly contaminated.

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Microgrids play an important role in stabilizing the electrical grid and they are the best route to develop green and sustainable energy. Since microgrids are expanding rapidly, it is necessary to consider the related control issues including power quality, bidirectional power flow, voltage and frequency control, and stability analysis. One of the main measurement challenges is the communication delay.

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Phase I Clinical Trial of Autologous Hematopoietic Stem Cell Transplantation-Supported Dose-Intensified Chemotherapy With Adebrelimab as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer.

Clin Lung Cancer

December 2024

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Department of Pulmonary and Critical Care Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:

Background: Small cell lung cancer (SCLC) is initially highly sensitive to chemotherapy, which often leads to significant tumor reduction. However, the majority of patients eventually develop resistance, and the disease is further complicated by its "cold" tumor microenvironment, characterized by low tumor immunogenicity and limited CD8+ T cell infiltration. These factors contribute to the poor response to immunotherapy in many cases of extensive-stage SCLC (ES-SCLC).

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