From the methanolic extract of the rhizomes of , a new flavanone derivative named (2,7″)-8-(1-phenyl-2-carboxyethyl)pinocembrin () and four known flavonoids (-) were isolated. Its absolute configuration was concluded by NMR and MS spectroscopic analysis, together with comparison between experimental and calculated ECD data. In turn, compound exhibited strong cytotoxicity against the PANC-1 human pancreatic cancer cell line with a PC value of 6.4 µM under nutrient-deprived conditions, comparable with that of arctigenin (PC, 0.83 µM).

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http://dx.doi.org/10.1080/14786419.2020.1837822DOI Listing

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