A signal transmission line and its characteristics were analyzed in detail for a beam-current monitor (CM) for long-pulsed electron beams. The monitor was based on a conventional current transformer, which comprised an induction coil wound around a ferrite core. The signal transmission and noise generation mechanism were analyzed by theoretical models based on balanced and unbalanced coaxial transmission circuits to effectively reduce noises superimposed on the beam-current signal waveform. The results of numerical analyses based on the theoretical models were in good agreement with those of an experiment for verification. It was found that the noise signals were generated by a high-power klystron operation and they were mode-transformed on the way to the transmission line. These results show that the locations of the grounded points in the transmission line were important. Based on a symmetrically configured three-line circuit theory, a new highly symmetrically configured coaxial transmission line is proposed to effectively suppress noises generated in CM. This report describes in detail the numerical and experimental analysis of a signal transmission line with coaxial cables for CM where the noise generation mechanism and its reduction technique are deeply involved.
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http://dx.doi.org/10.1063/5.0017729 | DOI Listing |
Background: Intrabdominal pressure (IAP) is an important parameter. Elevated IAP can reduce visceral perfusion, lead to intraabdominal hypertension, and result in life-threatening abdominal compartment syndrome. While ingestible capsular devices have been used for various abdominal diagnoses, their application in continuous IAP monitoring remains unproven.
View Article and Find Full Text PDFStem Cell Res Ther
January 2025
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, 212000, Jiangsu, P. R. China.
Background: Asthma is a prevalent respiratory disease, and its management remains largely unsatisfactory. Mesenchymal stem cells (MSCs) have been demonstrated to be efficacious in reducing airway inflammation in experimental allergic diseases, representing a potential alternative treatment for asthma. Migrasomes are recently identified extracellular vesicles (EVs) generated in migrating cells and facilitate intercellular communication.
View Article and Find Full Text PDFPlacenta
January 2025
Department of Pediatrics, Research Institute of the McGill University Health Center, Montreal, Quebec, Canada. Electronic address:
Introduction: Group B Streptococcus (GBS) is an opportunistic pathogen that can induce chorioamnionitis (CA), increasing the risk of neurodevelopmental disorders (NDDs) in the offspring. The placenta facilitates maternal-fetal communication through the release of extracellular vesicles (EVs), which may carry inflammatory molecules such as interleukin (IL)-1. Although the role of EVs in immune modulation is well established, their specific characterization in the context of GBS-induced CA has not yet been investigated.
View Article and Find Full Text PDFVitam Horm
January 2025
Department Normal Physiology, Yaroslavl State Medical University, Yaroslavl, Russia. Electronic address:
The hypothalamus, in addition to controlling the main body's vital functions, is also involved in aging regulation. The aging process in the hypothalamus is accompanied by disturbed intracellular pathways, including Ca signaling and neuronal excitability in the brain. Intrinsic electrophysiological properties of individual neurons and synaptic transmission between cells is disrupted in the central nervous system of old animals.
View Article and Find Full Text PDFBiosci Trends
January 2025
School of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Alzheimer's disease (AD) is the most common type of dementia. Its incidence is rising rapidly as the global population ages, leading to a significant social and economic burden. AD involves complex pathologies, including amyloid plaque accumulation, synaptic dysfunction, and neuroinflammation.
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