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Risk of Surgical Site Infection in Posterior Spine Surgery Using Different Closing Techniques: A Retrospective Study of Two Neurosurgical Centers.
J Clin Med
December 2024
Division of Neurosurgery, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1205 Geneva, Switzerland.
To determine whether a closed dressing protocol reduces the surgical site infections (SSI) rate compared to conventional closing techniques. Patients who underwent lumbar spine surgery at two neurosurgical centers were retrospectively included from June 2015 to December 2019. Data on patients, general risk factors, and surgical risk factors for SSI were collected.
View Article and Find Full Text PDFGallic acid-guar gum and chitosan-based polyelectrolyte complex film exhibited enhanced wound healing in full-thickness excision wound model.
J Biomater Sci Polym Ed
January 2025
Department of Medical Affairs, Curie Sciences, Samastipur, Bihar, India.
Article Synopsis
- Recent developments in wound dressings focus on natural bioactives like guar gum (GG) and gallic acid (GA), which can enhance healing compared to traditional materials.
- The study created a GA-GG conjugate through a polymerization process, confirming its successful integration and beneficial structural changes via various spectroscopic analyses.
- A polyelectrolyte complex (PEC) film made with chitosan showed strong antioxidant and antimicrobial properties, high swelling rates, and excellent wound healing efficacy, achieving 94.5% closure in comparison to untreated controls.
Growth, Body Composition, and Strength of Children With Cystic Fibrosis Treated With Elexacaftor/Tezacaftor/Ivacaftor (ETI).
Pediatr Pulmonol
January 2025
Pulmonary and Sleep Medicine, DeVos Children's Hospital, Grand Rapids, Michigan, USA.
Objective: We prospectively monitored rates of change for growth, body mass and composition, muscle strength, and FEV1 in 6-11-year-olds initiating ETI therapy, comparing them to those of US reference children. We assessed factors potentially contributing to rate of change and report ranges of individual variation.
Methods: Body composition was assessed using bioelectrical impedance analysis (BIA), and rates of change were analyzed using linear mixed effects regression models.
Lauric acid-loaded biomimetic, biocompatible, and antioxidant jelly fig (Ficus awkeotsang Makino) pectin hydrogel accelerates wound healing in diabetic rats.
Int J Biol Macromol
January 2025
Tissue Engineering and Biomaterials Laboratory, Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India. Electronic address:
Herein, we have presented a lauric acid (LA)-loaded jelly fig pectin (JFP)-based biocompatible hydrogel, which possesses strong antioxidant and antibacterial properties to treat diabetic wounds. The antioxidant and antibacterial activity of the JFP + LA hydrogels were beneficial in eliminating the reactive oxygen species (ROS) and bacterial infection in the wound bed, thereby protecting the wound surface and accelerating the tissue repair process. The in vivo diabetic wound healing studies demonstrated that applying JFP + LA hydrogels improved the rate of wound contraction and reduced the epithelialization time significantly.
View Article and Find Full Text PDFSargassum glaucescens Extract/Marine-Derived Collagen Blend Sponge and Their Properties for Wound Healing.
Mar Biotechnol (NY)
January 2025
Burn Research Center, Iran University of Medical Sciences, Tehran, Iran.
Burn wounds are challenging to treat due to considerable tissue damage and fluid loss. Creating wound dressings from natural and biological materials makes it possible to treat wounds and promote rapid epithelialization to speed healing and restore skin function. As a result, the ability of a collagen scaffold (Col) made from rainbow trout (Oncorhynchus mykiss) and putative bioactive phytochemical components from a Sargassum glaucescens (S.
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