The study objective was to determine the effects of PB6 and/or chromium propionate supplementation on health, growth performance, and carcass characteristics of high-risk beef cattle during a 56-d feedlot receiving period and the subsequent finishing period. Four truckload blocks of crossbred beef bulls ( = 300) and steers [ = 84; body weight (BW) = 220 ± 16.2 kg] were sourced from regional auction markets and assigned randomly to treatments arranged in a 2 × 2 factorial. The generalized complete block design consisted of 12 pen replications per treatment with pen as the experimental unit. Treatments were: 1) placebo control (CON); 2) 13 g per animal daily of PB6 (CST); 3) 450 ppb dry matter (DM) chromium propionate (CHR); and 4) 13 g per animal daily of PB6 and 450 ppb DM chromium propionate (CST + CHR). Treatments were top dressed in feed bunks daily using 0.45 kg per animal ground corn carrier immediately following feed delivery. Data were analyzed using mixed models. During the receiving period, dry matter intake (DMI) increased ( ≤ 0.03) for CST during each interim period. Overall receiving period daily DMI was 0.35 kg per animal greater for CST ( = 0.01). Cattle fed CST had greater ( ≤ 0.06) BW on days 14, 28, and 56. Likewise, average daily gain (ADG) was improved for CST from day 0 to 14 ( = 0.04) and for the overall receiving period (days 0-56; = 0.04). From days 0 to 14, CST tended ( 0.08) to increase gain:feed. During the finishing period, CHR reduced ( = 0.02) final BW and ADG (day 56 to final; = 0.01) and ADG was less for CHR over the entire feeding period (day 0 to final; = 0.03). The main effect of both CST ( = 0.02) and CHR ( = 0.03) decreased the overall treatment rate for bovine respiratory disease (BRD), and CST reduced overall antimicrobial treatment cost by $3.50 per animal compared to CON ( 0.03). Hot carcass weight (HCW) decreased ( = 0.01) in cattle fed CHR. The percentage of edible livers tended to increase (CST × CHR; = 0.08) in the CST treatment. Feed intake and growth performance outcomes during the receiving period were improved by CST but not CHR supplementation. However, both CST and CHR supplementation decreased the BRD morbidity rate. During the finishing period, performance and HCW were reduced in cattle supplemented with CHR.
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http://dx.doi.org/10.1093/tas/txaa163 | DOI Listing |
Otol Neurotol
February 2025
Department of ORL-Head & Neck Surgery and Audiology, Odense University Hospital, Odense C, Denmark.
Objective: To investigate the association between postoperative antibiotic prophylaxis and the risk of infections leading to implant explantation or hospitalization, with a follow-up of up to 12 years.
Study Design: Retrospective cohort study.
Setting: Tertiary medical institution.
PLoS One
January 2025
Worldwide Health Economics and Outcomes Research, Bristol Myers Squibb, Princeton, NJ, United States of America.
Background: Belatacept is approved for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients and is associated with a risk of post-transplant lymphoproliferative disorder (PTLD).
Methods: Data from the Organ Procurement and Transplantation Network were used to examine patterns of belatacept use, describe patient characteristics, and estimate risk of PTLD in EBV-seropositive, kidney-only transplant recipients receiving belatacept- or calcineurin inhibitor (CNI)-based immunosuppression as part of US Food and Drug Administration-mandated safety monitoring.
Results: During the study period (June 15, 2011-June 14, 2016), 94.
J Cogn Neurosci
January 2025
Shahid Beheshti University, Tehran, Iran.
Risk-taking is a prominent aspect of adolescent behavior. A recent neurodevelopmental model suggests that this trait could influence prosocial and antisocial decision-making, proposing a new category known as prosocial and antisocial risk-taking. The primary objective of this study was to examine the electrophysiological underpinnings of prosocial and antisocial risk-taking in adolescence, a developmental period characterized by elevated risky, prosocial, and antisocial decisions.
View Article and Find Full Text PDFDisabil Rehabil
January 2025
Amsterdam Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Purpose: (1) To evaluate the effectiveness of personalised psychologically-informed physiotherapy in people with neck pain; (2) To explore the mediating role of changes in illness perceptions.
Method: In this replicated single-case study, 14 patients with non-specific neck pain at risk for chronicity received a personalised intervention addressing unhelpful illness perceptions and dysfunctional movement behaviour, according to principles of cognitive functional therapy. Outcomes included the mediating role of illness perceptions on overall effect, function, pain intensity and self-efficacy.
J Cancer Res Ther
December 2024
Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P. R. China.
Background: Endoscopic submucosal dissection (ESD) is a standardized procedure for intramucosal and slightly invasive submucosal colorectal cancers (CRC). However, the role of ESD for T1b (depth of submucosal invasion: ≥1,000 μm) CRC remains unclear. This study aimed to investigate the long-term efficacy and safety of ESD for T1b CRC.
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