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| http://dx.doi.org/10.1097/HS9.0000000000000488 | DOI Listing |
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Multidimensional perspectives of geo-epidemiology: from interdisciplinary learning and research to cost-benefit oriented decision-making.
Front Public Health
January 2025
Biosecurity, Los Alamos National Laboratory, Los Alamos, NM, United States.
Research typically promotes two types of outcomes (inventions and discoveries), which induce a virtuous cycle: something suspected or desired (not previously demonstrated) may become known or feasible once a new tool or procedure is invented and, later, the use of this invention may discover new knowledge. Research also promotes the opposite sequence-from new knowledge to new inventions. This bidirectional process is observed in geo-referenced epidemiology-a field that relates to but may also differ from spatial epidemiology.
View Article and Find Full Text PDFObservation of the Clinical Efficacy of Self-Modified Skin-Stretching Device in the Treatment of Soft-Tissue Defects of the Heel: A Retrospective Single-Arm Cohort Study.
Orthop Surg
January 2025
Department of Orthopedics Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Objective: Due to the poor skin mobility of the heel, there are few reports on the efficacy and safety of skin-stretching devices in the treatment of soft-tissue defects of the heel. Redesigning the claws of the stretching devices may be one of the solutions to the problem. This study was designed to investigate the clinical effect of self-modified skin-stretching device in the treatment of soft-tissue defects in the heel.
View Article and Find Full Text PDFA multicenter micro-costing analysis of flexible cystoscopic procedures in Korea.
Investig Clin Urol
January 2025
Department of Spinal Neurosurgery, Gangnam Severance Hospital, Seoul, Korea.
Purpose: This study aims to develop and implement an economic evaluation using a micro-costing approach to provide a precise and transparent analysis of the direct costs of cystoscopic procedures in Korean hospitals. The study seeks to identify key cost components and evaluate whether current reimbursement rates accurately reflect these direct costs.
Materials And Methods: Significant variations in cost items were identified across different studies.
Revising EU pharmaceutical legislation: will it foster drug repurposing?
Drug Discov Today
January 2025
Department of Clinical Epidemiology & Medical Technology Assessment (KEMTA), Maastricht University Medical Centre, Maastricht, the Netherlands; Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands; REPO4EU consortium.
Repurposing off-patent drugs can be a potential source of low-cost treatments for patients with unmet medical needs. Here, we review the proposed new European Union (EU) pharmaceutical legislation in which two articles address drug repurposing. We find certain barriers hindering the adoption of these new incentives by academic and not-for-profit stakeholders, including lack of knowledge on regulatory aspects, pharmacovigilance, and restrictions in data protection.
View Article and Find Full Text PDFPayment Matters: Understanding Payer Perspectives on Laboratory Stewardship.
J Appl Lab Med
January 2025
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Background: The US healthcare system is complex and includes a number of entities and systems that provide services to patients and to pay for them. While improving health and well-being are accepted goals of healthcare, the 3 stakeholder groups relevant to healthcare-patients, providers, and payers-often have different perspectives on how care should be utilized, performed, and paid for. These differing perspectives are discussed as they relate to clinical laboratory testing.
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