Aim: The virulence of the novel coronavirus disease (COVID-19) has facilitated its rapid transition towards becoming a pandemic. Hence, this study aims to investigate the association between population migration and the number of confirmed COVID-19 cases in China while investigating its measures for pandemic prevention and control.
Subject And Methods: A susceptible-exposed-infected-recovered-dormancy (SEIRD) model for the spread of COVID-19 in China was created to theoretically simulate the relationship between the populations migrating from Wuhan and the number of confirmed cases. Data from Baidu's real-time dynamic pandemic monitoring system were elicited to empirically examine the theoretical inferences.
Results: Populations migrating from Wuhan to other cities increased the initial number of latently infected cases in these cities, raising the number of confirmed cases. Hence, implementing social distancing between the susceptible and infected populations could effectively lower the number of infected cases. Using data from Baidu's real-time dynamic pandemic monitoring system, the empirical results revealed that an increase of 1000 persons migrating from Wuhan raised the number of confirmed cases by 4.82 persons.
Conclusion: This study confirmed the positive association between population migration and the number of confirmed COVID-19 cases. Based on the theoretical and empirical analysis, China's pandemic prevention and control measures are discussed.
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http://dx.doi.org/10.1007/s10389-020-01403-y | DOI Listing |
Crit Care Explor
January 2025
All authors: Department of Pharmacy, Brigham and Women's Hospital, Boston, MA.
Importance: Recent studies have found an association between COVID-19 infection and deeper sedation in mechanically ventilated patients, raising concerns about the impact of the COVID-19 pandemic on pain, agitation, and delirium (PAD) management practices overall.
Objectives: This study aimed to assess differences in PAD management in patients without COVID-19 infection in pre- and peri-COVID-19 pandemic timeframes.
Design, Setting, And Participants: This was a single-center, retrospective, pre-/post-cohort analysis of mechanically ventilated adult patients without COVID-19 infection admitted to an ICU in Boston, MA.
Metab Brain Dis
January 2025
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700 032, India.
Alzheimer's disease is a complex neurodegenerative disease characterized by progressive decline in cognitive function and behaviour. Ginger is the rhizome of the plant Zingiber officinale Roscoe, has been an important ingredient of many Ayurveda formulations to treat neurological disorders. The present study aims to estimate the variation of 6-gingerol content in nine different ginger samples collected from Manipur, India, investigate the neuroprotective potential of the most potent ginger sample against scopolamine-induced cognitively impaired mice, and validate the therapeutic claim by molecular docking analysis.
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January 2025
The Dermatology Department of the Central Military Hospital of the Ministy of Defense, Baku, Azerbaijan.
The use of antidepressant medications in the treatment of lichen simplex chronicus (LSC) also known as neurodermatitis, is not well-documented in the literature. The primary aim of our study is to evaluate the impact of duloxetine 30 mg on the quality of life in patients with LSC, focusing on both pruritus and psychopathological aspects. The secondary aim is to investigate the relationship between LSC and anxiety and depression.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
The coronary slow flow phenomenon (CSF) causes persistent chest pains that can affect patients' quality of life. We aimed to examine the ranolazine impacts on clinical symptoms in CSF patients. The present randomized, double-blind, placebo-controlled trial consisted of 44 patients with CSF.
View Article and Find Full Text PDFFASEB J
January 2025
Department of Pharmacy, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by severe liver inflammation and fibrosis due to an imbalanced immune response caused by enhanced bacterial components. The progression of MASH is closely linked to increased permeability of intestinal mucosal barrier facilitating enter of bacterial components into hepatic portal venous system. B cells are important immune cells for adaptive responses and enhance hepatic inflammation through cytokine production and T cell activation.
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