The treatment of Blount's disease has historically remained controversial. All the described techniques for its treatment have their own advantages and disadvantages, and no consensus has been reached on a single surgical approach. The aim of this report is to share the early results of a combination technique in which we have collated three well-known surgical steps in one procedure. This combined procedure is indicated for severe and recurrent cases. Our 'three-in-one' technique combines an intra-epiphyseal plateau elevating osteotomy with a tibial metaphyseal osteotomy and a lateral tibial temporary hemi-epiphysiodesis. We also report initial results of three limbs in two patients who were treated using this technique. The first case was that of an adolescent with severe left Blount's disease (Langenskiold stage IV) and a lateral thrust. The second case was that of bilateral severe infantile Blount's disease (Langenskiold stage V) and the infant had a lateral thrust. All measurements remarkably improved in both patients during the post-surgical assessment. The limb length discrepancy was 0.6 cm in the first case and 0.5 cm in the second. The preoperative internal tibial rotation and lateral thrust were corrected spontaneously. No complications were recorded in either patient. The three-in-one technique is a safe and versatile surgical approach that can be used in severe, refractory, and recurrent cases of open physis. Furthermore, it can potentially solve the problems of lateral thrust and internal tibial rotation. More cases should be studied before we can endorse the safety and effectiveness of this technique.
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http://dx.doi.org/10.1016/j.jtumed.2020.08.002 | DOI Listing |
Circ Cardiovasc Interv
December 2024
Cardiovascular Clinical Research Center, Department of Medicine, NYU Grossman School of Medicine, New York, NY (H.R.R., L.P., S.B., J.S.H.).
Background: The relationship between the extent and severity of stress-induced ischemia and the extent and severity of anatomic coronary artery disease (CAD) in patients with obstructive CAD is multifactorial and includes the intensity of stress achieved, type of testing used, presence and extent of prior infarction, collateral blood flow, plaque characteristics, microvascular disease, coronary vasomotor tone, and genetic factors. Among chronic coronary disease participants with site-determined moderate or severe ischemia, we investigated associations between ischemia severity on stress testing and the extent of CAD on coronary computed tomography angiography.
Methods: Clinically indicated stress testing included nuclear imaging, echocardiography, cardiac magnetic resonance imaging, or nonimaging exercise tolerance test.
Introduction: The avoidance of asthma triggers, like tobacco smoke, facilitates asthma management. Reliance upon caregiver report of their child's environmental tobacco smoke (ETS) exposure may result in information bias and impaired asthma management. This analysis aimed to characterize the chronicity of ETS exposure, assess the validity of caregiver report of ETS exposure, and investigate the relationship between ETS exposure and asthma attack.
View Article and Find Full Text PDFACS Infect Dis
December 2024
Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover and develop. Herein, we report results for natural product-inspired novel tambjamine antimalarials. We show that they are potent against liver, asexual erythrocytic, and sexual erythrocytic parasite life cycle stages.
View Article and Find Full Text PDFOrthop Traumatol Surg Res
October 2024
Institut du Mouvement et de l'appareil Locomoteur, Hôpital Sainte-Marguerite, Aix-Marseille Université, Marseille, France. Electronic address:
Background: Tibial condylar valgus osteotomy (TCVO), or Chiba osteotomy, is a recognized procedure for treating advanced knee osteoarthritis in middle-aged individuals. Although its effectiveness is established, limited literature exists on its outcomes for specific conditions such as post-traumatic deformities, Blount disease (BD), and Pagoda-like proximal tibia varus deformities.
Hypothesis: We hypothesized that TCVO could improve both clinical and radiographic outcomes in patients with severe varus deformities, correcting lower-limb variances while preserving joint line obliquity (JLO) and patellar height in substantial varus deformities.
A case of locally acquired (autochthonous) mosquito-transmitted Plasmodium vivax malaria was diagnosed in Arkansas in September 2023. This represents the 10th autochthonous case identified nationally in 2023, after 20 years without recorded local mosquitoborne malaria transmission in the United States. The public health response included case investigation, active case surveillance, mosquito surveillance and control, assessment of medical countermeasures, and clinical and public outreach.
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