Objective: Single-stage sequential bilateral video-assisted thoracoscopic surgery (VATS) is a controversial procedure. In the present study, we retrospectively compared the outcomes of single-stage and two-stage VATS.

Methods: This study involved patients who underwent single-stage sequential bilateral VATS (SS-VATS group) or two-stage VATS at a 3-month interval (TS-VATS group) for treatment of non-small cell lung cancer from 2010 to 2018. The major outcome was the comparison of intraoperative changes.

Results: The inspiratory peak pressure was higher, the incidences of intraoperative hypoxia and unstable hemodynamics were higher, the surgical time was longer, and the durations of the intensive care unit stay and postoperative hospitalization were longer in the SS-VATS group than in the TS-VATS group. However, the chest tube duration, incidence of postoperative mechanical ventilation, and clinical complications were not different between the two groups.

Conclusions: Compared with two-stage VATS, single-stage sequential bilateral VATS can be performed for successful treatment of bilateral pulmonary lesions with a shorter total time and higher cost-effectiveness in terms of anesthesia and hospitalization but with a higher incidence of intraoperative adverse effects and a longer hospital stay.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653298PMC
http://dx.doi.org/10.1177/0300060520967558DOI Listing

Publication Analysis

Top Keywords

single-stage sequential
12
sequential bilateral
12
single-stage two-stage
8
bilateral video-assisted
8
bilateral vats
8
ss-vats group
8
two-stage vats
8
ts-vats group
8
bilateral
5
vats
5

Similar Publications

Co-products from the frozen fish processing industry often lead to financial losses. Therefore, it is essential to transform these co-products into profitable goods. This study explores the production of fish protein hydrolysates (FPH) from three co-products: the heads and bones of black scabbardfish (), the carcasses of gilthead seabream (), and the trimmings of Nile perch ().

View Article and Find Full Text PDF

A recent study design for clinical trials with small sample sizes is the small n, sequential, multiple assignment, randomized trial (snSMART). An snSMART design has been previously proposed to compare the efficacy of two dose levels versus placebo. In such a trial, participants are initially randomized to receive either low dose, high dose or placebo in stage 1.

View Article and Find Full Text PDF

Background: The incidence of revision shoulder arthroplasty continues to rise, and infection is a common indication for revision surgery. Treatment of periprosthetic joint infection (PJI) in the shoulder remains a controversial topic, with the literature reporting varying methodologies, including the use of debridement and implant retention, single-stage and 2-stage surgeries, antibiotic spacers, and resection arthroplasty. Single-stage revision has been shown to have a low rate of recurrent infection, making it more favorable because it precludes the morbidity of a 2-stage operation.

View Article and Find Full Text PDF

Adaptive randomization methods for sequential multiple assignment randomized trials (smarts) via thompson sampling.

Biometrics

October 2024

Department of Statistical Science, Duke University, 214 Old Chemistry, Box 90251, Durham, NC 27708-0251, United States.

Response-adaptive randomization (RAR) has been studied extensively in conventional, single-stage clinical trials, where it has been shown to yield ethical and statistical benefits, especially in trials with many treatment arms. However, RAR and its potential benefits are understudied in sequential multiple assignment randomized trials (SMARTs), which are the gold-standard trial design for evaluation of multi-stage treatment regimes. We propose a suite of RAR algorithms for SMARTs based on Thompson Sampling (TS), a widely used RAR method in single-stage trials in which treatment randomization probabilities are aligned with the estimated probability that the treatment is optimal.

View Article and Find Full Text PDF

The study evaluated the performance of thermophilic co-digestion in both single-stage methanogenic reactors (TMR) and two-stage systems, consisting of a thermophilic acidogenic reactor and a thermophilic sequential methanogenic reactor (TSMR). A 1:1 mixture of sugarcane vinasse and molasses was codigested in anaerobic fluidized bed reactors, with varying organic matter concentrations based on chemical oxygen demand (COD) ranging from 5 to 22.5 g COD L.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!