The article deals with some problematic aspects of the legal protection of the human embryo and fetus. It is established that according to the legislation of Ukraine a live-born child will be considered a subject of legal relations irrespective of the week of pregnancy and state of health. Various scientific legal and medical approaches to the issue of completing the period of embryonic development have been investigated. The positions of scientists on the legal protection of embryos, which were conceived using reproductive technologies, namely, until their implementation in the body of the future mother, are analyzed. It is proved that all embryos need special protection, regardless of the method of their conception, and it has also been established that various manipulations with embryos are prohibited in order to conduct medical experiments. Foreign experience of legislative regulation of the beginning of life is investigated. It is established that in Ukraine the civil capacity of a natural person arises at the moment of its birth, but in the cases established by law, the interests of a conceived but not born child are protected. The case-law of the European Court of Human Rights on the protection of the «unborn life» is analyzed. It is proposed to characterize the legal status of «embryo» and «human fetus» as «subjective», which provides for separate elements of legal protection, and in the case of transition to a subjective state - protection of property rights, the grounds for which occurred during the «pre-subject» of the «state». The necessity to establish in the legislation of Ukraine a uniform approach to the determination of the period of embryonic development and its completion, as well as the corresponding changes to Part 2 of Art. 2 of the Law of Ukraine «On Prohibition of Human Reproductive Cloning».
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Clin Rheumatol
January 2025
Department of Pediatric Rheumatology, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey.
Introduction/objectives: The study aimed to determine whether in children with newly diagnosed juvenile idiopathic arthritis (JIA) hepatitis B surface antibody (anti-HBs) differs from healthy children and to see whether the revaccination is safe and effective under JIA treatment.
Methods: Patients who were followed up with a diagnosis of JIA between January 2020 and February 2024 were included. The control group consisted of healthy children matched for age and gender.
BMJ Open
December 2024
Drugs for Neglected Diseases initiative, Geneva, Switzerland
Introduction: The Drugs for Neglected Diseases initiative (DNDi) is committed to maximising the scientific value of the individual participant data (IPD) it has collected during its 20 years of activity and the IPD it will collect in the future, while safeguarding research participants' privacy and their right to know how their data will be processed.
Objective: The objective of this article is to share what DNDi has learnt while working on its commitment to data sharing. It also aims to advance the debate about best practice in the research community to avoid 'IPD sharing paralysis', with a focus on multistakeholder projects involving patients and researchers based in countries with various levels of data privacy regulations and measures.
BMJ Open
December 2024
PMV Research Group, Medical Faculty and University Hospital Cologne, University of Cologne, Koln, Germany
Introduction: In Germany, there has been no population-level pharmacoepidemiological study on the safety of the COVID-19 vaccines. One factor preventing such a study so far relates to challenges combining the different relevant data bodies on vaccination with suitable outcome data, specifically statutory health insurance claims data. Individual identifiers used across these data bodies are of unknown quality and reliability for data linkage.
View Article and Find Full Text PDFHealth Res Policy Syst
January 2025
Centre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.
During public health crises such as pandemics, governments must rapidly adopt and implement wide-reaching policies and programs ("public policy interventions"). A key takeaway from the coronavirus disease 2019 (COVID-19) pandemic was that although numerous randomized controlled trials (RCTs) focussed on drugs and vaccines, few policy experiments were conducted to evaluate effects of public policy interventions across various sectors on viral transmission and other consequences. Moreover, many quasi-experimental studies were of spurious quality, thus proving unhelpful for informing public policy.
View Article and Find Full Text PDFSci Rep
January 2025
Institute For Chengdu-Chongqing Economic Zone Development, Chongqing Technology and Business University, Chongqing, 400067, China.
This study explores the residents' behavioral determinants of ecological conservation in rural tourism development, focusing on resident participation to promote sustainable development in the tourism industry. By integrating the Theory of Planned Behavior (TPB) and the Norm Activation Model (NAM), it examines the roles of subjective norm, responsibility attribution, ecological environmental risk perception, and human capital in shaping ecological conservation behavior. Based on data from 331 valid responses collected through a questionnaire survey, structural equation model (SEM) was performed using SPSS and AMOS to analyze ecological conservation behavior.
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