Determination of the I activity in the thyroid of exposed people or workers is one of the major concerns that needs to be addressed following a nuclear or radiological emergency. International intercomparison exercises on bioassay measurements are one of the effective methods to improve the capability and quality of internal dose assessment. In 2017, Working Group 1 (Internal Dosimetry) of the Asian Radiation Dosimetry Group (ARADOS) organized an intercomparison exercise on the thyroid measurement, aiming at enhancing and coordinating the radiation dosimetry capabilities of Asian countries. This paper describes the measurement experience and results of In Vivo Monitoring Laboratory of NIRP in the 2017 intercomparison exercise, which can provide technical reference for laboratories that have not yet participated in such thyroid measurement intercomparsion. It covers technical aspects such as calibration, measurement and data processing. The results presented in this intercomparison are within an acceptable range of performance criteria on the bioassay measurements. In addition, further research work considered in the field of thyroid measurement is described in the discussion section.
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http://dx.doi.org/10.1016/j.apradiso.2020.109492 | DOI Listing |
J Pediatr Endocrinol Metab
January 2025
Department of Pediatric Pulmonology, Dicle University, Diyarbakır, Türkiye.
Objectives: There is limited research on thyroid function in pediatric patients with cystic fibrosis (pwCF). This study aimed to determine the frequency of thyroid dysfunction in children and adolescents with CF and to evaluate iodine deficiency and selenium status in pwCF.
Methods: Sixty-two CF patients and 62 control subjects were evaluated.
Curr Mol Med
January 2025
Department of Anesthesiology, Baoan Central Hospital of Shenzhen, Shenzhen, Guangdong Province, China.
Background: Morphine, a mu-opioid receptor (MOR) agonist commonly utilized in clinical settings alongside chemotherapy to manage chronic pain in cancer patients, has exhibited contradictory effects on cancer, displaying specificity toward certain cancer types and doses.
Objective: The aim of this study was to conduct a systematic assessment and comparison of the impacts of morphine on three distinct cancer models in a preclinical setting.
Methods: Viability and apoptosis assays were conducted on a panel of cancer cell lines following treatment with morphine, chemotherapy drugs alone, or their combination.
Int J Gen Med
January 2025
Division of Endocrinology and Metabolism, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan.
Purpose: Glucose metabolism is associated with several endocrine disorders. Anti-diabetes drugs are crucial in controlling diabetes and its complications; nevertheless, few studies have been carried out involving endocrine function. This study aimed to investigate the association between anti-diabetes drugs and endocrine parameters.
View Article and Find Full Text PDFCureus
December 2024
Department of Oral Medicine and Radiology, Drs Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Vijayawada, IND.
Background The thyroid gland is the most susceptible organ to radiation during the exposure of teeth because the thyroid area appears to be within the primary beam, and the dose levels are relatively high even after using collimation. This study aims to develop an eco-friendly thyroid shield by reusing lead foils from intra-oral periapical radiographic films and evaluate its effectiveness in intraoral radiography. Methods A total of 16 patients undergoing endodontic procedures who gave written consent to participate in the study were included and divided into four categories: anterior, canine, premolar, and molar.
View Article and Find Full Text PDFNarra J
December 2024
Department of Physiology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia.
Iodine has an anti-proliferative effect on cancer cells; however, its effects have not been explored adequately. The aim of this study was to evaluate the therapeutic potential of iodine and radioiodine by assessing their effects on the viability of various breast cancer cell lines: MCF7, SKBR3, and MDA-MB231. The viability of cells was measured in treated cells exposed to six doses of iodine (5, 10, 20, 40, 60, 80 µM) and two doses of radioiodine (3.
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