Ozone injection therapy for intervertebral disc herniation.

Introduction: Lumbar disc herniation (LDH) is a common cause of low back pain (LBP). Recently, in the setting of LBP caused by LDH, a growing interest in ozone therapies has been observed.

Source Of Data: Recent published literatures.

Areas Of Agreement: Being low back pain more common in the elderlies, exploring conservative alternatives to the surgical intervention is of especial interest.

Areas Of Controversy: Efficacy and feasibility of ozone injections for LDH is debated. Several clinical studies showed controversial results, and the true benefit has not yet been clarified.

Growing Points: Systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy for LDH.

Areas Timely For Developing Research: Current evidence encourage the use of ozone therapy for LBP from LDH. These conclusions should be interpret in light of the limitations of the present study.