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Course of Sars-CoV2 Infection in Patients with Cancer Treated with anti-PD-1: A Case Presentation and Review of the Literature. | LitMetric

AI Article Synopsis

  • * A case study is presented of a metastatic melanoma patient who had been successfully treated with anti PD-1 therapy and contracted COVID-19, ultimately recovering fully.
  • * A review of existing literature indicates limited evidence, but suggests it's possible for cancer patients on immunotherapy to continue their treatment while managing COVID-19.

Article Abstract

The outbreak of COVID-19 pandemia is a major health worldwide concern. Patients with cancer might have a worse outcome, because of the immunosuppression determined by the tumor itself and anti-cancer treatments, including chemotherapy and radiotherapy. The impact and course of viral infection in patients receiving immunotherapy remains unknown. We report the case of a patient with metastatic melanoma, long responder to anti PD-1 blockade who got infected with Sars CoV-2, recovering without sequelae. A critical review of literature was performed. Limited data available in literature support the possibility to continue the immunotherapy in patients with cancer under control.

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Source
http://dx.doi.org/10.1080/07357907.2020.1844893DOI Listing

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