Objective: The rise of zoonotic diseases has become a global health issue around the world. The present study is aimed at assessing the global status and the trends in scrub typhus (ST) research.
Methods: Publications related to ST studies from 1945 to 21 July 2020 were retrieved from the Scopus database. The search for the ST literature was conducted using the entry terms of the MeSH (Medical Subject Headings) database. Full research articles and reviews were included in the analysis, and no limitation to the language was specified. Key bibliometric indicator analysis was performed using Microsoft Excel, Bibliometrix (an R package), GraphPad Prism 5, and VOSviewer (version 1.6.6).
Results: A total of 1567 publications were retrieved. The results revealed a significant increase in the number of ST publications over time. The documents received an average of 11.22 citations per document. Mahidol University in Thailand (258, 16.46%) was the most productive institution, while the published the most ST articles (88, 5.62%). Korea (195, 12.44%) was the most productive country, followed by India (178, 11.36%) and China (106, 6.76%). Richards AL was the most productive author with 36 articles.
Conclusions: The study findings provide useful insights into the global efforts and works related to the progress of ST research, which can be used to identify future research areas, such as vaccine development.
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http://dx.doi.org/10.1155/2020/5737893 | DOI Listing |
J Clin Med
December 2024
Department of Internal Medicine, Division of Infectious Disease, Soonchunhyang University Hospital, Cheonan 31151, Republic of Korea.
: This study explores the potential of using elevated levels of blood double-stranded RNA (dsRNA) as a diagnostic tool for severe fever with thrombocytopenia syndrome (SFTS) infection. : Blood samples from SFTS patients were collected, dsRNA was purified, and total dsRNA expression was quantitatively analyzed using a spiropyran-based method. Comparative analysis was performed using blood samples from healthy individuals and scrub typhus patients with similar symptoms.
View Article and Find Full Text PDFTravel Med Infect Dis
January 2025
Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, Yunnan, China; Yunnan Key Specialty of Pediatric Infection (Training and Education Program)/Kunming Key Specialty of Pediatric Infection; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address:
Acta Trop
January 2025
All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India, 273008. Electronic address:
Scrub typhus (ST) is an emerging public health concern in India. Despite being treatable, 20-30% of acute febrile illnesses (AFI) progress to encephalitis in endemic regions. This study aimed to identify early markers for encephalitis development in children hospitalized with AFI and positive Orientia tsutsugamushi (Ots) serology.
View Article and Find Full Text PDFInfect Chemother
December 2024
Division of Infectious Diseases, Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
Tsutsugamushi disease is a febrile mite-borne disease caused by . Before 1945, this disease had been prevalent in Niigata, Akita, and Yamagata prefectures for centuries, occurring in areas along major rivers in these prefectures every summer about a month after floods. The patients affected were farmers, possibly new settlers on reclaimed lands, who contracted the disease following bites of tiny red bugs.
View Article and Find Full Text PDFIndian Pediatr
January 2025
ICMR Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India. Correspondence to: Dr Manoj Murhekar, Director-in-Charge, ICMR-Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India 273013.
Objective: To estimate the proportion of children with acute febrile illness (AFI) attending the peripheral health facilities in Gorakhpur, Uttar Pradesh, India, due to Orientia tsutsugamushi (Ots) and re-evaluate the strategy of presumptive administration of doxycycline/azithromycin (PDA) to patients with AFI.
Methods: Children aged 2-18 years with AFI attending 16 peripheral health facilities in Gorakhpur, Uttar Pradesh, were enrolled in September 2023. Blood samples were tested for O.
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