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Evaluation of Xanthine Oxidase Inhibitors Febuxostat and Allopurinol on Kidney Dysfunction and Histological Damage in Two-Kidney, One-Clip (2K1C) Rats.
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Department of Pharmaceutical Sciences, North South University, Dhaka, Bangladesh.
In chronic kidney disease (CKD), hyperuricemia is a common phenomenon, presumably due to reduced renal clearance of uric acid. This study investigated the effect of xanthine oxidase (XO) inhibitors allopurinol and febuxostat to prevent oxidative stress in the kidney of two-kidney, one-clip (2K1C) rats. In this investigation, 2K1C rats were used as an experimental animal model for kidney dysfunction.
View Article and Find Full Text PDFAnticancer activity of , a rare and endemic species of holly in Northeast India, against murine lymphoma.
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DBT-BUILDER National Laboratory, Department of Life Sciences, Pachhunga University College, Aizawl, 796001, Mizoram, India.
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Key Comprehensive Laboratory of Forestry, Northwest A&F University, Yangling, Shaanxi Province, 712100, P. R. China.
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View Article and Find Full Text PDFPhytotoxic impact of di-butyl phthalate (DBP) on physiological, biochemical, and oxidative stress parameters of rice (Oryza sativa).
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Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
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Chongqing Key Laboratory of High Active Traditional Chinese Drug Delivery System, Chongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing 401331, PR China. Electronic address:
Small-molecule pectin (SMP) extracted from the leaves of Premna ligustroides Hemsl, with a molecular weight range of 5000-35,000 Da, has demonstrated anti-inflammatory and lipid-lowering properties in vitro. This study explored the effects of SMP on hypercholesterolemia in mice, with a focus on inflammation, lipid profiles, and cholesterol metabolism. Mice received SMP at doses of 607, 303, and 152 mg/kg body weight.
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