Modern Blood Culture: Management Decisions and Method Options.

Clin Lab Med

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, 117 South 11th Street, Pavilion Building Suite 207, Philadelphia, PA 19107-4998, USA. Electronic address:

Published: December 2020

The optimal care of septic patients depends on the successful recovery of clinically relevant microorganisms from blood cultures and the timely reporting of organism identification and antimicrobial susceptibility testing (AST) results. Many preanalytic factors play a critical role in culturing microorganisms, and advancements in blood culture instrument technology have reduced the time to positive results. Additionally, rapid organism identification and AST results directly from positive blood culture broth via new methods help to further shorten the time from empiric to targeted treatment. This article summarizes the current state of blood culture methods, including preanalytic, analytical, and postanalytic factors that are available to clinical microbiology laboratories.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501519PMC
http://dx.doi.org/10.1016/j.cll.2020.07.001DOI Listing

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