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Functional performance of a vibrotactile sensory substitution device in people with profound vision loss.
Optom Vis Sci
June 2024
Department of Physiotherapy, University of Melbourne, Melbourne, Victoria, Australia.
Significance: This study has shown a vibrotactile sensory substitution device (SSD) prototype, VibroSight, has the potential to improve functional outcomes (i.e., obstacle avoidance, face detection) for people with profound vision loss, even with brief familiarization (<20 minutes).
View Article and Find Full Text PDFProfiling cell-type specific gene expression in post-mortem human brain samples through laser capture microdissection.
Methods
November 2022
McGill Group for Suicide Studies, Douglas Hospital Research Center, Montreal, QC H4H 1R3, Canada; Department of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada. Electronic address:
The transcriptome of a cell constitutes an essential piece of cellular identity and contributes to the multifaceted complexity and heterogeneity of cell-types within the mammalian brain. Thus, while a wealth of studies have investigated transcriptomic alterations underlying the pathophysiology of diseases of the brain, their use of bulk-tissue homogenates makes it difficult to tease apart whether observed differences are explained by disease state or cellular composition. Cell-type-specific enrichment strategies are, therefore, crucial in the context of gene expression profiling.
View Article and Find Full Text PDFElectrocution Due to Fractal Wood Burning: Two Case Reports and a Review of the Medical Literature.
Am J Forensic Med Pathol
December 2022
Preclinical Education, Lake Erie College of Osteopathic Medicine, Erie, PA.
Fractal wood burning is a new technique of pyrography that passes an electrical current through a piece of wood resulting in decorative electrical burns. This practice has become increasingly popular with many walk-through tutorials of the process found online. This includes videos of how to build homemade devices fashioned from disassembled microwave oven transformers.
View Article and Find Full Text PDFFever of Unknown Origin: The Workup and Diagnosis of Pel-Ebstein Fever.
Cureus
February 2022
Business Management, Grand Canyon University, Phoenix, USA.
The clinical and diagnostic workup of fever of unknown origin (FUO) is key in the treatment of patients on the internal medicine service. In this article, the authors present a case of fever of unknown origin, walk through the differential diagnosis, explain the laboratory testing ordered in the workup of the patient as well as the resulting values of said testing, and discuss the pathophysiology and diagnostic criteria for the diagnosis of Pel-Ebstein fever. The authors also discuss a clinical pearl when working with electronic health records to ensure that the needs of the patient in question are met.
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