A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Attempt to read property "Count" on bool

Filename: helpers/my_audit_helper.php

Line Number: 3100

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Endovascular treatment and cognitive outcome after anterior circulation ischemic stroke. | LitMetric

AI Article Synopsis

  • - The study investigated how endovascular treatment (EVT) affects cognitive outcomes in patients who had anterior circulation ischemic strokes, particularly comparing those treated with only intravenous thrombolysis (IVT) to those receiving both EVT and IVT.
  • - A total of 88 patients participated, and cognitive abilities were assessed six months after the stroke using various neuropsychological tests, revealing that those who received EVT plus IVT had significantly better cognitive performance than those who only received IVT.
  • - The results indicated that EVT was independently associated with improved cognitive function, even after controlling for other factors like age, gender, and initial stroke severity, with notable improvements seen in executive functions, attention, and memory.

Article Abstract

The impact of reperfusion therapies on cognition has been poorly explored and little knowledge exists. We explored the influence of endovascular treatment (EVT) on cognitive outcome in patients with anterior circulation ischemic stroke. Patients presenting with ischemic stroke due to anterior large vessel occlusion who underwent intravenous thrombolysis (IVT) alone or EVT plus IVT were recruited. Cognitive abilities were evaluated at 6 months from stroke through a neuropsychological test battery. A total of 88 patients with a mean age of 66.3 ± 12.9 years were included, of which 38 treated with IVT alone and 50 with IVT plus EVT. Compared to patients treated with IVT alone, patients who received EVT plus IVT performed significantly better at the neuropsychological tests exploring executive functions, attention, abstract reasoning, visuospatial ability, visual and verbal and memory. At multivariable regression analysis, the EVT was independently associated with the 6-month cognitive performance after the adjustment for age, sex, admission National Institutes of Health Stroke Scale score, systolic blood pressure, glucose level, Alberta Stroke Program Early CT score, side of stroke, site of occlusion, and Back Depression Inventory score [Stroop Test Word Reading: β = 13.99, 95% confidence interval (CI) 8.47-19.50, p < 0.001; Stroop Test Colour Naming: β = 6.63, 95% CI 2.46-10.81, p = 0.002; Trail Making Test-A: β = - 92.98, 95% CI - 153.76 to - 32.20, p = 0.003; Trail Making Test-B: β = - 181.12, 95% CI - 266.09 to - 96.15; p < 0.001; Digit Span Test Forward: β = 1.44, 95% CI 0.77-2.10, p < 0.001; Digit Span Test Backward: β = 1.10, 95% CI 0.42-1.77, p = 0.002; Coloured Progressive Matrices: β = 5.82, 95% CI 2.71-8.93, p < 0.001; Rey Complex Figure Test-Copy: β = 6.02, 95% CI 2.74-9.30, p < 0.001; Rey Complex Figure Test-Immediate recall: β = 6.00, 95% CI 2.34-9.66, p = 0.002; Rey Complex Figure Test-Delayed recall: β = 5.73, 95% CI 1.95-9.51, p = 0.003; Rey Auditory Verbal Learning Test-Immediate recall: β = 12.60, 95% CI 6.69-18.52, p < 0.001; Rey Auditory Verbal Learning Test-Delayed recall: β = 1.85, 95% CI 0.24-3.45, p = 0.025]. Patients treated with EVT plus IVT had better cognitive performance than patients treated with IVT alone at 6 months from anterior circulation ischemic stroke.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595128PMC
http://dx.doi.org/10.1038/s41598-020-75609-1DOI Listing

Publication Analysis

Top Keywords

ischemic stroke
12
endovascular treatment
8
cognitive outcome
8
anterior circulation
8
circulation ischemic
8
ivt evt
8
evt ivt
8
treated ivt
8
stroke
7
ivt
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!