AI Article Synopsis
- * Intravascular hemolysis was identified as the reason for her AKI, indicated by findings from a renal biopsy showing acute tubular injury and hemosiderin deposits.
- * The patient's renal function and blood conditions improved with increased glucocorticoid dosage, hemodialysis, and plasma exchange, highlighting the need to monitor renal health in severe hemolysis cases.
Article Abstract
A 65-year-old woman with systemic sclerosis and systemic lupus erythematosus developed acute kidney injury (AKI), Coombs-positive autoimmune hemolytic anemia and autoimmune thrombocytopenia; therefore, she was diagnosed with Evans syndrome (ES). Intravascular hemolysis was suggested as the cause of AKI based on the presence of acute tubular injury and trace hemosiderin deposits on the renal biopsy. The renal function, hemolytic anemia and thrombocytopenia were restored by an increased dose of glucocorticoids, hemodialysis, and plasma exchange. Although ES with severe hemolytic anemia is very rare, it is important to detect possible renal dysfunction when encountering patients with severe hemolysis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079912 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.5976-20 | DOI Listing |
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