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http://dx.doi.org/10.1017/ice.2020.1305 | DOI Listing |
Int J Impot Res
January 2025
Department of Urology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Sildenafil is one of the most used phosphodiesterase type 5 inhibitor (PDE5i) for the treatment of erectile dysfunction (ED) in clinical practice. A new oral suspension formulation (OSF) of sildenafil has been introduced to overcome the drawbacks of previous formulations. We assess the efficacy and patients' experience with sildenafil 50 mg OSF in men with ED who were taking the sildenafil oro-dispersible film (ODF).
View Article and Find Full Text PDFBMJ Open
January 2025
School of Psychology, Newcastle University, Newcastle upon Tyne, UK
Objective: Shared medical appointments (SMAs) are an innovative care delivery method that provides delivery of clinical care while also supporting self-management. Their usefulness for mental health conditions has only briefly been explored, though early evidence demonstrates their utility for supporting mental health management. Therefore, this study set out to better understand the views that adults with anxiety and depression have towards SMAs as a way of receiving care to support self-management in primary care.
View Article and Find Full Text PDFSci Total Environ
January 2025
Material Flow Management and Resource Economy, Institute IWAR, Technical University of Darmstadt, Franziska-Braun-Straße 7, 64287 Darmstadt, Germany.
Nutrient circularity, an exemplification of circular economy (CE), is situated in the waste/wastewater-agriculture nexus. Recycling nutrient elements from waste streams to fertilizer products amplify the sustainable management of resources and intersect technical and biological loops, a concept developed for CE. Such a complex system needs to be directed by robust assessment methods such as life cycle assessment (LCA) to identify trade-offs and potentials.
View Article and Find Full Text PDFBiochem Cell Biol
January 2025
Department of Histology and Embryology, School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen, China.
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease with high mortality and limited treatment options. While single-dose bleomycin-induced models are commonly used to investigate the pathogenesis of IPF, they fail to adequately replicate the complex pathological features in human patients, thereby hindering comprehensive investigations. Previous studies utilizing repetitive bleomycin injections have demonstrated a closer resemblance to human IPF pathology; however, the time- and resource-intensive nature of this approach presents significant drawbacks.
View Article and Find Full Text PDFHeliyon
January 2025
Biomass Conversion and Bioproducts Laboratory, Center for Bioenergy, School of Chemical & Biotechnology, SASTRA Deemed University, Thirumalaisamudram, Tamil Nadu, India.
Plastic pollution is a worrying problem, and its degradation is a laborious process. Although enzymatic plastic breakdown is a sustainable method, drawbacks such as numerous plastic kinds of waste make the degradation challenging. Therefore, a multi-plastic degrading (MPD) enzyme becomes necessary.
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