Is there a role for childhood vaccination against COVID-19?

Pediatr Allergy Immunol

Center for Vaccinology, University Hospitals of Geneva, Geneva, Switzerland.

Published: January 2021

Tremendous efforts are undertaken to quickly develop COVID-19 vaccines that protect vulnerable individuals from severe disease and thereby limit the health and socioeconomic impacts of the pandemic. Potential candidates are tested in adult populations, and questions arise of whether COVID-19 vaccination should be implemented in children. Compared to adults, the incidence and disease severity of COVID-19 are low in children, and despite their infectiveness, their role in disease propagation is limited. Therefore, COVID-19 vaccines will need to have fully demonstrated safety and efficacy in preventing not only complications but transmission to justify childhood vaccination. This work summarizes currently tested vaccine platforms and debates practical and ethical considerations for their potential use in children. It also discusses the already deleterious effect of the pandemic on routine childhood vaccine coverage, calling for action to limit the risks for a rise in vaccine-preventable diseases.

Download full-text PDF

Source
http://dx.doi.org/10.1111/pai.13401DOI Listing

Publication Analysis

Top Keywords

childhood vaccination
8
covid-19 vaccines
8
role childhood
4
vaccination covid-19?
4
covid-19? tremendous
4
tremendous efforts
4
efforts undertaken
4
undertaken develop
4
covid-19
4
develop covid-19
4

Similar Publications

Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost.

Nat Commun

January 2025

Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Neutralizing antibody titer has been a surrogate endpoint for guiding COVID-19 vaccine approval and use, although the pandemic's evolution and the introduction of variant-adapted vaccine boosters raise questions as to this surrogate's contemporary performance. For 985 recipients of an mRNA second bivalent or monovalent booster containing various Spike inserts [Prototype (Ancestral), Beta, Delta, and/or Omicron BA.1 or BA.

View Article and Find Full Text PDF

Introduction: Risk factors for COVID-19 hospitalization in children include incomplete vaccination and having high-risk chronic conditions. There is concern for a lack of vaccine equity. Our study evaluates the association between socioeconomic child opportunity index (COI), chronic conditions, and vaccine uptake.

View Article and Find Full Text PDF

Danish parents' vaccination readiness is associated with their children's officially registered vaccination history.

Vaccine

January 2025

Department of Psychology, University of Copenhagen, Copenhagen, Denmark; Copenhagen Center for Social Data Science (SODAS), University of Copenhagen, Copenhagen, Denmark; Faculty of Psychology, University of Vienna, Vienna, Austria.

Previous research has shown that parents' vaccination readiness, as measured by the 7C vaccination readiness scale, helps to understand whether and why parents are (not) willing to vaccinate their children. However, there is a lack of research investigating the association between parents' vaccination readiness and their children's actual vaccine uptake. Addressing this gap, we examined how Danish parents' level of vaccination readiness is associated with their child's vaccination status combining survey with official registry data.

View Article and Find Full Text PDF

Understanding the cultural influences on parents in Saudi Arabia regarding adherence to childhood vaccination programs is crucial for the health and safety of the whole society. This study aims to explore the impact of cultural factors on parents' attitudes toward vaccinating children before school age. A systematic review and meta-analysis were conducted on cross-sectional and interventional studies.

View Article and Find Full Text PDF

A protective effect of childhood vaccinations on leukemia risk, particularly acute lymphoblastic leukemia (ALL), has been hypothesized, though findings are inconsistent. We used a nationwide cohort of Danish children born 1997-2018 (n = 1,360,230), to examine associations between childhood vaccinations and leukemia (<20 years) using registry data (follow-up: December 31, 2018). Cox proportional hazard models with age as the underlying time estimated hazard ratios (HRs) for leukemia (any, ALL, acute myeloid [AML], and other), comparing vaccinated with unvaccinated children.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!