Background: Information is presented about cholera as an infectious disease and an epidemic in Polish lands and in Europe in 1831 based on old and modern sources.
Objective: To analyze the difference in the percentages of deaths from cholera depending on age, in the Tuliszków parish during the cholera epidemic in 1831.
Material And Methods: A query was carried out in the archives. Information on deaths between 1829 and 1839 was obtained from the parish registry files. The following factors were taken into account: the cause of death, the age of the deceased and the place of residence. For individual age groups, the numbers of people who died of cholera in 1831 and those who died from other causes in the control year 1835 were compared by the Fisher test. The GBL and PubMed database was searched using the keywords: cholera, cholera epidemic, deaths, Tuliszków, the year 1831, Holy Spirit Hospital, Konin.
Results: An outbreak of cholera in Tuliszków parish in 1831 began around the 8th of August and lasted until about the 10th of October. 81 people died of cholera: 74 people in Tuliszków and 7 people in Sarbicko. The number of deaths in infants and children up to 5 years of age was in fact significantly lower than in other age groups (p = 0.0052). The percentage of deaths from cholera compared to deaths from other causes among infants and children under 5 years of age decreased from 52.46% to 28.4%. In the age group of 20 to 40 years old it increased from 13.11% to 23.46% and in the age group over 55 years from 9.84% to 19.75%.
Conclusions: In Tuliszków parish in 1831, the number of deaths of infants and children under 5 years of age caused by cholera was indeed significantly lower than in other age groups (p = 0.0052).
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.32394/pe.74.13 | DOI Listing |
Colomb Med (Cali)
January 2025
Universidad Internacional del Ecuador UIDE, School of Medicine, Quito, Ecuador Universidad Internacional del Ecuador Universidad Internacional del Ecuador School of Medicine Quito Ecuador.
Background: Differences in asthma prevalence between urban and rural areas have been observed worldwide. Epidemiological studies in middle- and low-income countries suggest that internal migration processes may partly explain these disparities.
Objective: To investigate the association between internal migration and asthma in children living in transitional areas of Ecuador.
PLoS Pathog
January 2025
Department of Cancer and Genomic Sciences, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.
Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to create an environment that is supportive of a productive and persistent infection. The virus-induced changes to the host cell's transcriptome are thought to contribute to carcinogenesis. Here, we show by RNA-sequencing that oncogenic HPV18 episome replication in primary human foreskin keratinocytes (HFKs) drives host transcriptional changes that are consistent between multiple HFK donors.
View Article and Find Full Text PDFSequestration of parasites in the placental vasculature causes increased morbidity and mortality in pregnant compared to non-pregnant patients in malaria- endemic regions. In this study, outbred pregnant CD1 mice with semi allogeneic fetuses were infected with transgenic or mock-inoculated by mosquito bite at either embryonic day (E) 6 (first trimester-equivalent) or 10 (second trimester- equivalent) and compared with non-pregnant females. -infected mosquitoes had greater biting avidity for E10 dams than uninfected mosquitoes, which was not apparent for E6 dams nor non-pregnant females.
View Article and Find Full Text PDFJ Comput Chem
January 2025
Department of Chemistry, Gottwald Center for the Sciences, University of Richmond, Richmond, Virginia, USA.
The energies and geometries of the lowest lying singlet and triplet states of the four diradicals formed by removing two H atoms from thiophene have been characterized. We utilized the highly correlated, multireference methods configuration interaction with single and double excitations with and without the Pople correction for size-extensivity (MR-CISD+Q and MR-CISD) and averaged quadratic coupled cluster theory (MR-AQCC). CAS (8,7) and CAS (10,8) active spaces involving σ, σ*, π, and π* orbitals were employed along with the cc-pVDZ and cc-pVTZ basis sets.
View Article and Find Full Text PDFVaccines (Basel)
January 2025
CBRN, Biomedical Advanced Research & Development Authority (BARDA), Administration for Strategic Preparedness and Response (ASPR), U.S. Department of Health and Human Services (HHS), Washington, DC 20201, USA.
Over the past few decades, the world has seen a considerable uptick in the number of new and emerging infectious disease outbreaks. The development of new vaccines, vaccine technologies, and platforms are critical to enhance our preparedness for biological threats and prevent future pandemics. Viral vectors can be an important tool in the repertoire of technologies available to develop effective vaccines against new and emerging infectious diseases.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!